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ID:19783967
大小:4.40 MB
页数:63页
时间:2018-10-06
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1、SkeletalTuberculosis(Part-2)Dr.SunilAroraJuniorResidentDeptt.ofChest&TBGovt.MedicalCollege,Patiala.11IntroductionSkeletalTBaccountsfor10to35%ofcasesofextrapulmonarytuberculosis.Althoughspineisthecommonestsite(constitutingabout50%)ofskeletalTB.Theotherbonesandjointsc
2、analsobeinvolved.SkeletalTBgenerallyoccursduetohaematogenousspreadfromaprimaryfocus.2ClassificationTUBERCULARARTHRITIS-30%HIPJOINTKNEEWRISTJOINTSACROILIACJOINTANKLEJOINTANDFOOTSHOULDERJOINTTUBERCULAROSTEOMYELITIS-19%LONGTUBULARBONESSHORTTUBULARBONESFLATBONES-RIBS,ST
3、ERNUM,SCAPULA,PELVISTENOSYNOVITIS/BURSITIS-1%3PathogenesisItproducessimilarresponseasinlungsi.e.Chronicgranulomatousinflammation.Thediseaseprocesscanstarteitherinboneorinthesynovialmembrane.Activefocusformsinthemetaphysis(inchildren)orepiphysis(inadults)andtheinflam
4、mationextendsperipherallyalongtheshafttoreachthesubperiostealspace.Theinflammatoryexudatemayextendoutwardthroughthesofttissuetoformcoldabscessandsinuses.Theaffectedbonemayundergofracture.4Metaphysealinfectionreachesthejointthroughsubperiostealspacebypenetratingtheca
5、psularattachment.Inadults,theinflammationcanspreaduptothesubchondralareaandenterthejointattheperipherywheresynoviumjoinsthecartilagewhichleadstothelooseningtheattachmentofarticularcartilageandjointdisplacement.5Sometimesthesynoviumisinfectedfirstandtheboneisinfected
6、secondarily.Itisusuallyintheformoflow-gradesynovitiswiththickeningofthesynovialmembraneandleadingtotheformationofpannus.Eventually,thearticularcartilageisdestroyed,jointgetsdistendedwithpus,whichmayburstouttoformacoldabscessordischargingsinus.Thejointmayalsogetsublu
7、xatedduetothelaxityofthejointcapsuleandligaments.Fibrousankylosisisacommonoutcomeofhealedtuberculosisofthejointsexceptinspinewherebonyankylosisfollowsmoreoften.6TypesTwoclassicalformsofdiseasehavebeenseen;granularandandexudative(caseous)thatinvolvetheboneandsynovium
8、.BoththepatternshavebeenobservedinpatientsofskeletalTB,oneformmaypredominate.1.Osseousgranulartype:--oftenfollowstrauma-insidiousonset,con
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