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1、早中期非创伤性股骨头坏死中医药保髋疗效影响因素分析*何海军1刘波2林坤弟1刘道兵1陈卫衡1Δ(1.中国中医学院望京医院,北京,100102;2.贵阳中医学院,贵阳,550002)【摘要】目的:总结并分析影响早中期非创伤性股骨头坏死中医药保髋治疗的疗效影响相关因素,为提高临床效果提供理论依据。方法:选取经中国中医科学院望京医院骨关节三科住院接受中医药保髋治疗,随访时间超过一年的早中期(ARCOII-IIIa期)非创伤性股骨头坏死,影像学检查结果为加重的患者30例,设为加重组;随机选取同期在我科住院接受相同治疗方法,影像学检查结果稳定的早中期非创伤性ONFH患者30例,设为
2、稳定组。通过Excel表格,采用双人双录,专人核对的方式,收集两组患者的临床病历资料,分析并比较两组患者在年龄、性别、职业、体重指数、病程、饮酒史、激素使用史、拄拐因素方面的差异性。结果:加重组与稳定组在年龄、体重指数、性别比率及末次随访Harris评分比较上,差异均无统计学意义(P>0.05);加重组病程为4.10(±2.09)年,高于稳定组的2.66(±1.39)年,差异有统计学意义(P<0.05);加重组体力劳动者为70%,与稳定组的43.3%相比,差异有统计学意义(P<0.05);加重组酒精致病因素为43.3%,明显低于稳定组的70%(P<0.05);加重组激素
3、致病因素为56.7%,明显高于稳定组的30%(P<0.05);结论:职业、病程、饮酒史、激素使用史、拄拐因素对早中期非创伤性股骨头坏死保髋治疗疗效影响明显,治疗中需加以重视。【关键词】非创伤性;股骨头坏死;中医药保髋;疗效影响因素AnalysisofinfluencingfactorsoftheefficacyofTCMhip-preservinginearly-to-middlestagenon-traumaticosteonecrosisofthefemoralheadLIUbo1LINkundi2HEhaijun2SHENdanqing1WANGzhentao1C
4、HENweiheng2Δ(1.GuiyangCollegeofTraditionalChineseMedicine,Guiyang,550002,China;2.WangjingHospitalofChinaAcademyofChineseMedicalSciences,Beijing,100102,China)【Abstract】Objective:TosummarizeandanalyzerelatedinfluencingfactorsoftheefficacyofTCMhip-preservinginearly-to-middlestagenon-traumat
5、icosteonecrosisofthefemoralhead(ONFH).Methods:ThirtyinpatientsonTCMhip-preservingtreatmentattheThirdDepartmentofOsteoarthropathy,WangjingHospital,CACMS,wereassignedtotheaggravatedgroup,whowerefollowedupforearly-to-middlestage(ARCOstageII-IIIa)non-traumaticONFHoveramorethanone-yearperioda
6、nddiagnosedasaggravatedbyimageologicalfindings.Additional30inpatientsonthesametreatmentatthesamehospitalwereassignedtothestablegroup,whowerediagnosedasstableearly-to-middlestagenon-traumaticONFHbyimageologicalfindings.WithExcel,clinicaldataofmedicalrecordswerecollectedfrombothgroupsofpat
7、ientsusingdoubleentryandvalidation.Differenceswerecomparedbetweenbothgroupswithrespecttoage,gender,occupation,bodymassindex(BMI),course,drinkinghistory,historyofsteroiduseandfactorofbeingoncrutches.Results:FollowingTCMhip-preserving,amonginfluencingfactorsoftheefficacyofT