七年制医学课件 耳鼻喉 4喉癌

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1、1.Preface(1)Themostcommonestcarcinomainthelarynx(2)Thegreatdifferencefromplacetoplace(3)Thegreatdifferencebetweenmaleandfemalemale:female10:1(4)Themostdangerousage:50~70喉癌carcinomaoflarynx2.Etiology,unclear(1)smoking(2)drinking(3)aircontaintment(4)virusinfectionHPV(5)hormone(6)pre-malignantle

2、isions(癌前病变)papillomaofthelarynx(喉乳头状瘤)leukoplakiaofthelarynx(喉白班病)正常喉部MultiplepapillomasofthelarynxPapillomatosisofthelarynxPapillomaofthelarynxPapillomaofthelarynxandtracheaLeukoplakiawithdysplasiaofthevocalcordsChronicparakeratoticlaryngitis3.Pathology93%~99%squamouscellcarcinomabetterdiff

3、erentiated(I-II)4.Clinicalsymptomsandsignssupraglotticcarcinoma声门上型癌glotticcarcinoma声门型癌subglotticcarcinoma声门下型癌(1)supraglotticcarcinomaA.earlystage:(atypical)haemoptysis(痰中带血)Sorethroat（喉痛）Irritatingcough(刺激性咳嗽)B.laterstage:Hoarsness（声嘶）Dyspnea（呼吸困难）C.easilylymphnodematastases(淋巴结转移)Carcinom

4、aoftheepiglottisAdvancedsquamouscellcarcinomaofthelarynx(2)glotticcarcinomaA.earlystagehoarsnessB.laterstagedyspnea(呼吸困难)C.difficultymatastases(3)sybglotticcarcinomasameassupraglotticcarcinomaCarcinomainsituoftheleftvocalcordCarcinomaoftheanteriorglottisSquamouscellcarcinomaofthearyepiglottic

5、foldandpiriformsinus5.Diaglosisbiopsy（活检）x-ray、CT-scan、MRI6.Treatment(1)operation(手术)partiallaryngectomy（部分喉切除术）totallaryngectomy（全喉切除术）(2)radiatherapy（放射治疗）(3)chemotherapy（化学治疗）