先天性心脏病概论黄国英课件

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1、HUANGGuoying（黄国英）DepartmentofPediatricsFudanUniversityShanghaiMedicalSchoolChildren’sHospitalofFudanUniversityCardiovascularDiseasesinChildren（Conspectus）TheAimofThisClassTounderstandtheclassificationofCHDToknowwelltheembryologicaldevelopmentofheart,causesofCHDanditspathogenesisToknowwelltheappr

2、oachesofevaluationofCHDToknowthecharacteristicsoffetalcirculation&changesafterbirthTohaveageneralideaaboutcardiovasculardiseasesinchildren,andtheprincipleoftreatmentofCHDChildren’sHospitalFoundedin1952ProfessorCHENCuizhenCardiovascularDiseasesinChildrenCongenitalheartdiseaseViralmyocarditisRheumat

3、icheartdiseaseCardiomyopathyKawasakiDiseaseArrhythmiaCongestiveheartfailurePericarditisInfectiveendocarditisEtc….EmbyologicalDevelopmentofHeartFormationofprimitivehearttubeLoopingofprimitivehearttubeFormationofendocardialcushionFormationofinteratrialseptumFormationofinterventricularseptumSeptation

4、ofaorticandpulmonaryarteriesFormationandLoopingofPrimitiveHeartTubeFormationofEndocardialCushionAVcanalposteriorrightAVorificeanteriorleftAVorificeFormationofEndocardialCushionSeptationofAtriaandVentriclesostiumprimum1＝LA胚胎第3周胚胎第4周胚胎第5-6周胚胎第7-8周2＝LV3＝RA4＝RV5＝septumprimum6＝septumsecundum7＝endocardi

5、alcushionostiumsecundumforamenovale8,9＝ventricularseptaInterventricularforamenSeptationofAtriaSeptationofVentriclesIVSiscomposedofthreeparts：①muscularseptum②cushioncomponent③A-PseptumcomponentSeptationofGreatArteriesAOPAPAAOPAPAAOAOPAAOPAPAPAPAMalpositionofGreatArteriesTOFTGADORVTaussig-BingEvolve

6、mentofArterialArchesobsoletesoonafterbirthcarotidarteriessubclavianA.brachiocephalicA.ductusarteriosusbranchesofpulmonaryartery1stpair2ndpair3rdpair4thpair5thpair6thpairFetalCirculation&ChangesafterBirthafterbirthbeforebirthCongenitalHeartDiseasesDefinition：Cardiovascularmalformationspresentdurin

7、gembryonicstages（胚胎期发生的心血管畸形）Prevalence：－7~8/1000newborns（reporteddata）－6.87/1000newbornsinShanghai（epidemiologicsurveyduring1989～1991）EtiologicConsiderationsHereditaryfactorsTrisomiesofchromosome21,18,13CATCH22s