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时间:2018-10-04
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1、2016IDSA念珠菌病指南ClinicalPracticeGuidelinefortheManagementofCandidiasis:2016UpdatebytheInfectiousDiseasesSocietyofAmericaI.Whatisthetreatmentforcandidemiainnonneutropenicpatients?(菌血症-非粒缺)II.Shouldcentralvenouscathetersberemovedinnonneutropenicpatientswithcandidemia?(是否拔除导管-非粒缺菌血症)II
2、I.Whatisthetreatmentforcandidemiainneutropenicpatients?(菌血症-粒缺)IV.Whatisthetreatmentforchronicdisseminated(hepatosplenic)candidiasis?(慢性播散性念珠菌病)V.Whatistheroleofempirictreatmentforsuspectedinvasivecandidiasisinnonneutropenicpatientsintheintensivecareunit?(ICU中经验性治疗非粒缺念珠菌病的地位)目录VI.
3、Shouldprophylaxisbeusedtopreventinvasivecandidiasisintheintensivecareunitsetting?(ICU预防)VII.Whatisthetreatmentforneonatalcandidiasis,includingcentralnervoussysteminfection?(新生儿,包括中枢神经系统)VIII.Whatisthetreatmentforintra-abdominalcandidiasis?(腹腔)IX.DoestheisolationofCandidaspeciesfro
4、mtherespiratorytractrequireantifungaltherapy?(呼吸道分离出是否要治疗)X.WhatisthetreatmentforCandidaintravascularinfections,includingendocarditisandinfectionsofimplantablecardiacdevices?(血管内感染,包括感染性心内膜炎、植入式心脏设备)目录XI.WhatisthetreatmentforCandidaosteoarticularinfections?(骨关节)XII.Whatisthetreatm
5、entforCandidaendophthalmitis?(眼内炎)XIII.Whatisthetreatmentforcentralnervoussystemcandidiasis?(中枢神经系统)XIV.WhatisthetreatmentforurinarytractinfectionsduetoCandidaspecies?(泌尿道生殖道)XV.Whatisthetreatmentforvulvovaginalcandidiasis?(外阴阴道)XVI.Whatisthetreatmentfororopharyngealcandidiasis?(口
6、咽部)XVII.Whatisthetreatmentforesophagealcandidiasis?(食管)目录推荐分级分级推荐强度Strong强Weak弱依据可靠性High++++Moderate+++Low++Verylow+常见念珠菌属对抗真菌药的折点白念珠菌氟康唑伊曲康唑伏立康唑泊沙康唑阿尼芬净卡泊芬净米卡芬净S≤2≤0.12≤0.12≤0.25≤0.25≤0.25SDD40.25-0.5I0.25-0.50.50.50.5R≥8≥1≥1≥1≥1≥1光滑氟康唑伊曲康唑伏立康唑泊沙康唑阿尼芬净卡泊芬净米卡芬净S≤0.12≤0.12≤0.06SDD3
7、2I0.250.250.12R≥64≥0.5≥0.5≥0.25常见念珠菌属对抗真菌药的折点近平滑氟康唑伊曲康唑伏立康唑泊沙康唑阿尼芬净卡泊芬净米卡芬净S≤2≤0.12≤2≤2≤2SDD4I0.25-0.5444R≥8≥1≥8≥8≥8热带氟康唑伊曲康唑伏立康唑泊沙康唑阿尼芬净卡泊芬净米卡芬净S≤2≤0.12≤0.25≤0.25≤0.25SDD4I0.25-0.50.50.50.5R≥8≥1≥1≥1≥1常见念珠菌属对抗真菌药的折点克柔氟康唑伊曲康唑伏立康唑泊沙康唑阿尼芬净卡泊芬净米卡芬净S≤0.5≤0.25≤0.25≤0.25SDDI10.50.50.5R≥2
8、≥1≥1≥1病情或治疗分组治疗首选可选非粒细胞缺乏念珠菌血症201
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