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1、HumanSchistosome(人体血吸虫)2007-11-7DiseaseduetoschistosomesistermedschistosomiasisorbilharziaaftertheshortlivedGermanphysicianTheodorBilharz(1825-1862).http://www.dpd.cdc.gov/dpdx/HTML/Schistosomiasis.htmKingdom:AnimaliaPhylum:PlatyhelminthesClass:TrematodaSubclass:D
2、igeneaOrder:Stringeiformes Genus:SchistosomaSpecies:Schistosomahaematobium,S.japonicum,S.mansoniandS.intercalatumhttp://www.schisto.org/Schistosomiasis/Default.htmSchistosome:Aparasitictrematodewormcontractedfrominfestedwaterthatiscapableofcausingliver,gastrointes
3、tinaltractandbladderdisease.Therearethreemainspeciesofthesetrematodeworms(flukes)--Schistosomahaematobium,Schistosomajaponicum,SchistosomamansoniandS.intercalatumthatproducediseaseinhumans.Endemicin74developingcountrieswithmorethan80%ofinfectedpeoplelivinginsub-Sa
4、haranAfrica.S.haematobiumisthemostprevalentandwidespreadspeciesinAfricaandtheMiddleEastS.intercalatumoccursin10countriesintherainforestbeltofAfricaS.mansoniisfoundinAfricaandistheonlyspeciesseeninLatinAmericaS.japonicumisrestrictedtothePacificregionincludingChinaa
5、ndthePhilippinesS.mekongiisfoundinlimitedareasofLaosandCambodia.S.japonicum,S.haematobium,S.mansoni,S.intercalatum,S.mekongiHumanSchistosomes:S.japonicum(日本血吸虫)S.mansoni(曼氏血吸虫)S.haematobium(埃及血吸虫)S.mekongi(湄公血吸虫)S.japonicumnamedbyKatsuradain1904In1905,firstcasefou
6、ndinHumanThediscoveryhistoryofSchistosomesS.haematobiumeggswerefoundinthekidneysoftwentieth-dynastyEgyptianmummies(1250-1000B.C)ThefirstEuropeanstorecordcontactwithS.haematobiumweresurgeonswithNapoleon'sarmyinEgypt(1799-1801).In1858(or1852),Weinlandproposedthename
7、Schistosomahaematobium.In1905,SirPatrickMansonfoundanotherspeciesofworm,namedS.mansonibySanbon(1907)In2005,0.799millioncasesLakeareas:humancases,snailinfestedareas,andnumberofinfectedbovineswasaccountingfor87.5%、94.4%、68.8%,respectivelyDistributioninChina一定要消灭血吸虫病
8、MorphologyLifecyclePathogenesis&clinicalmanifestationDiagnosisEpidemiologyPrevention&controlSchistosome:causativeagentofschistosomiasisLifecycle:adultwo
