口腔颌面外科学(中山大学)10口腔颌面部感染课件

口腔颌面外科学(中山大学)10口腔颌面部感染课件

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时间:2018-10-01

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1、OralandmaxillofacialinfectionLiangYu-jieDepartmentoforalandmaxillofacialsurgeryGuanghuaschoolofstomatologyKeypointsinclinicalpracticeAnatomyClinicalmanifestationAntibioticsBasicknowledgeAnatomyImmunologySurgeryLogicinfection&inflammationinfection&contagionlocal&sy

2、stemic/genetalacute&chronicIntroduction◆Infection:thepathologicalstateresultingfromtheinvasionofthebodybypathogenicmicroorganisms◆Inflammation:thereactionofbodytotheinvasionofthesemicroorganismsandthetoxinsgeneratedbythem.Thereactioninclude:alteration,exudation,pr

3、oliferationImmuneresponseintheearlystageofinjuryGreenantibodybattlesaredantigen!◆existenceofnormalbacterialflora◆open,suitablemoistureandtemperature(oralcavityandsinus,tooth,gingival,tonsillar)Characterisitcsoforal&maxillofacialregionCharacterisitcsoforal&maxillof

4、acialregion◆fasciaspace◆abundantbloodcirculation,andvalvelessveinsCharacterisitcsoforal&maxillofacialregion◆abundantlymphadenCharacterisitcsoforal&maxillofacialregionModesofTransmissionReasonsofinfection◆Odontogenicperiapicalperiodontitis,pulpitis,periodontitis◆Ad

5、enogenouslymphadenitis,parotitis◆Traumatic◆Hemogenic◆IatrogenicinfectionWhatcausesinfectiousdiseases?MicroorganismsBacteriaVirusPrionFungusProtozoaHelminthProductsfrommicroorganismstoxinsPathogenicbacteria◆staphylococcus,streptococcus,escherichiacoli◆aerobic,anaer

6、obic,mixedinfections◆Thegeneralinfectionprocessarethemixedflora:earlyphasetheaerobicbactericconsumetheavailableoxygen,allowstheovergrowthofanaerobesPathogenicbacteriaAnaerobicAnaerobicAreallbacteriabad?No!Somebacteriaperformessentialfunctionsinthebodysuchas:skin:p

7、reventsmoreharmfulbacteriafromcolonizingintestines:helpsbodybreakdownandabsorbcertainnutrients;preventsmoreharmfulbacteriafromcausingintestinalinfectionsvagina:preventsyeastsfromovergrowingandcausinginfectionsOtherbodyareasarecolonizedandinfectionsonlyoccurinimmun

8、ocompromisedpeoplenasopharynx,oropharynx,esophagus,stomachWhydopeoplegetsick?HostFactorsagegenderethnicityimmunestatusnutritionalstatusbehaviorBalanceis

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