小肠间质瘤46例临床特点及治疗

《小肠间质瘤46例临床特点及治疗》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。

1、小肠间质瘤46例临床特点及治疗作者：林克荣，刘建强，张志坚　　【Abstract】AIM:Toexploretheclinicalcharacteristicsanddiagnosisandtherapeuticmethodofgastrointestinalstromaltumorsofthesmallintestine.METHODS:Clinicaldataof46casesofgastrointestinalstromaltumorsofthesmallintestineadmitted199206/200606wereanalyzedretrospectively.The

2、diagnosiswasconfirmedpathologicallyforallcases.RESULTS:Gastrointestinalstromaltumorsofthesmallintestineattackedbothmaleandfemale,withthemaletofemaleratioas1.21∶1.Theageofthepatientsrangedfrom19to80(average53)years.Theagestagewiththehighestoccurrenceratelocatedat45-60years.Themajorclinicalsignsin

3、cluded:abdomenpain,abdomenmass,anaemiaandsmallbowelobstruction.Thegastrointestinalstromaltumorsofthesmallintestinehadpredilectioninthejejunumandduodenum.ThedetectionratecouldbeenhancedbyPETCT.Themosteffectivetherapywasoperationremovalofthetumors.Glivecmightbehelpfulforpatientswhohadpalliativeop

4、erationorinpreventingrecurrence.Reoperationcouldprolongthepatientssurvival,whohadlocalrecurrenceordistantmetastasis.7CONCLUSION:Theclinicalmanifestationsofgastrointestinalstromaltumorsofthesmallintestinearenonspecific.Thedetectionratecanbeimprovedbyrationalauxiliaryexaminations.Themosteffective

5、therapyisoperationremoval.　　【Keywords】mesothelioma;intestinalneoplasms;intestine,small　　【摘要】目的：探讨小肠间质瘤的临床表现、诊断及治疗方法.方法：对199206/200606收治的46例小肠间质瘤的临床资料进行回顾性分析，所有病例均经手术和病理证实.结果：小肠间质瘤男女均有发病，男女比为1.21∶1.本组发病年龄19～80(平均53)岁,45～60岁年龄段发病率最高.腹痛、腹部包块、贫血、小肠梗阻是本组最常见的临床表现.小肠间质瘤多好发于空肠和十二指肠，PETCT可提高小肠间质瘤检出率.手

6、术彻底切除病变，格列卫对于姑息手术者或对预防术后复发有较好的疗效.对复发或远处转移者再次手术可延长生存期.结论：小肠间质瘤临床表现缺乏特异性；合理应用辅助检查方法可提高小肠间质瘤检出率；手术为本病目前的最佳选择.　　【关键词】间皮瘤；肠肿瘤；小肠　　0引言　　胃肠道间质瘤(gastrointestinalstromaltumor,7GIST)是一种发生于消化道，起源于胃肠道壁Cajal细胞（ICC）或与Cajal细胞同源的间叶干细胞的梭形细胞肿瘤，发病率约2/10万，平均发病年龄约60岁［1］.GIST大多发生在胃，占60%～70%，小肠仅占20%～30%［2-3］.小肠间质瘤（gas

7、trointestinalstromaltumorsofthesmallintestine）早期的临床症状、体征缺乏特异性，容易延误诊治.我院199206/200606收治小肠间质瘤患者46例，现将临床诊治情况报告如下.　　1对象和方法　　1.1对象199206/200606收治小肠间质瘤46例，男25例，女21例；年龄19～80（平均53）岁.首诊以腹痛为主18例；腹部包块12例；贫血8例；肠梗阻6例.所有患者中有腹痛症状的29例.查