资源描述:
《不同氧流量对上腹部手术全身麻醉患者苏醒期的影响》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、不同氧流量对上腹部手术全身麻醉患者苏醒期的影响作者:赵连英 类维富 吴小鹏【摘要】目的:探讨不同氧流量机械通气对外科手术全麻病人苏醒期的影响。方法:择期全麻下行腹部手术病人48例,ASAⅠ~Ⅱ级,年龄33~68岁,平均50.5岁。随机分为3组,每组16例。Ⅰ组,于手术结束前30分钟开始降低安氟醚用量,每10~15min降低0.3~0.5vol%,术毕维持基准氧流量(2L/min)不变,Ⅱ组,术毕氧流量4L/min,Ⅲ组,术毕氧流量10L/min,其余各呼吸参数保持不变。术中连续监测血压、心率、心电图及脉搏血氧饱和度,连续监测吸入安氟醚浓度(F
2、i)和呼气末安氟醚浓度(Fa),记录停吸前即刻安氟醚浓度(Fao)及每隔1min的Fa,直至苏醒,并计算各时点的Fa/Fao;记录苏醒时间,并对所有病人术前和术后进行简易精神评分。结果:Ⅰ组患者Fa/Fao与Ⅱ、Ⅲ组相比有明显统计学差异;简易精神评分Ⅰ组与Ⅱ组、Ⅲ组相比有统计学意义;苏醒时间各组之间无统计学差异。结论:全麻苏醒期维持基准氧流量不变,有可能降低苏醒期谵妄发生率,但不影响外科手术全麻病人苏醒时间。【关键词】外科手术·麻醉药,吸入·苏醒·谵妄【ABSTRACT】Objective:Toinvestigateeffectsof10di
3、fferentfrashgasflowofoxygenventilationonemergencetimeanddeliriumundergoingEnfluranegeneralanesthesia.Methods:Forty-eightpatients,ASAⅠ-Ⅱ,aged33-68yr,mean50.5yr,underwentelectiveabdominaloperationwererandomlydividedintothreegroupsaccordingtothedifferentfrashgasflowattheendofo
4、peration:GroupⅠ,theflowofoxygenmaintainedat2L/min,GroupⅡ4L/min,GroupⅢ10L/min.Anesthesiawasinducedwithintravenousmidazolam0.08-0.1mg/kg,etomidate15-20mg,fentanyl3-4μg/kg,pipecuronium0.08-0.1mg/kgandmaintainedwithEnflurane(1.5-2.0vol%),supplementedwithintermittentivpipecuroni
5、umandfentanyl.TheconcentrationofEnfluranewasmonitoredcontinuouswhichinvolvedFi,FaandFao,originatedfrominspiration,expirationandthemomentexpirationwhenstoppedinhalation.AccountedFaoandafterthisdetailedeveryoneminuteFauntilthepatientsrecoveryandcalculatedFa/Faoratio.Emergence
6、timewasrecorded.Mini-MentalStateExamination(MMSE)wasperformedbeforeanesthesiaandaftersurgery.Results:Fa/FaoratioinGroupⅠwassignificantlydefferentfromGroupⅡandⅢ.MMSEscoresinGroupⅠwerehighercomparewithGroupⅡandⅢaftersurgery.Emergencetimewasnosignificantlydifferenceamongthreeg
7、roups.Conclusion:Thefrashgaslowflowofoxygen10ventilationmightreducetheincidenceofdelirium,butdoesnotinfluncethetimeofemergencefromgeneralanesthesia.【KEYWORDS】Surgicalprocedures,operative·Anesthesia,inhalation·Emergence·Delirium 吸入麻醉药是目前唯一同时具有镇静、镇痛和一定肌肉松驰作用的全身性麻醉药,因而得到广泛使用。
8、腹部外科手术除要求术中完善的肌肉松弛和稳定的血流动力学外,还要求术后平稳的苏醒。越来越多的文献报道吸入麻醉与术后患者意识谵妄及躁动有着密切的相关性[1-4]。Roh