躯体化障碍患者神经认知功能比较

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1、躯体化障碍患者神经认知功能比较【摘要】目的：探讨躯体化障碍患者神经认知功能障碍的特点。方法：对60例符合ICD-10躯体化障碍诊断标准的患者给予药物治疗8周，在治疗前、后给予威斯康星卡片分类测验（WCST）、持续操作测验（CPT），同时测验50例正常人作为对照组。患者组的测验结果进行自身前后比较、并分别与正常对照组进行组间比较。结果：患者组治疗前、后WCST的总应答数、完成分类数、持续性错误数、非持续性错误数自身比较，差异有统计学意义(P＜0.05～0.01)。患者组治疗前WCST的总应答数、完成分类数、持续性错误数、非持续性错误数与

2、正常对照组组间比较，差异有统计学意义(P＜0.01～0.001)，治疗后与正常对照组组间比较，差异无统计学意义(P＞0.05)。患者组治疗前、后CPT得分比较，在无干扰时差异无统计学意义(P＞0.05)，有干扰时差异有统计学意义(P＜0.05)。患者组治疗前CPT得分与正常对照组组间比较，在无干扰时差异无统计学意义(P＞0.05)，有干扰时差异有统计学意义(P＜0.05)，治疗后与正常对照组比较，差异无统计学意义(P＞0.05)。结论：躯体化障碍患者存在神经认知功能障碍，但经过治疗可以改善。【关键词】躯体化障碍；神经认知功能；威斯康星

3、卡片分类测验；持续操作测验Comparisonofneurocognitivefunctioninpatientswithsomatizationdisorder〔Abstract〕Objective:Toexploretheneurocognitivefunctioninpatientswithsomatizationdisorder.Methods:sixtysomatizationdisorderpatientswhomettheICD-10weretreatedfor8weeks,theyweremeasuredwithWis

4、consinCardSortingTest(WCST)andContinuousperformanceTest（CPT）beforeandaftertherapy.AndfiftyhealthypeoplesweremeasuredwithWCSTandCPTascontrolgroup.Thetestresultsofpatientsgroupwerecomparedbeforeandaftertherapy,andtheywerecomparedwiththecontrolgrouprespectively.Results:The

5、significantdifferenceinthetotaltrials,numberofcompletedclassification,preservativeerrors,nor-preservativeerrorsofWCSTwereobservedbetweembeforeandaftertherapyofpatientsgroup(P＜0.05～0.01).Andthesameresultswasalsofoundbetweenpatientsgroupbefortherapyandcontrolgroup（p＜0.05）

6、.Andnosignificantdifferencewasalsofoundbetweenpatientsgroupaftertherapyandcontrolgroup（p＞0.05）.ComparedtheCPTscoresbetweenpatientsgroupofbeforeandaftertherapy,thesignificantdifferencewasn’tfoundinnointerferestimulus(P＞0.05）,buttheycouldbefoundininterferestimulus(P＜0.05)

7、.Andthesameresultsalsobefoundbetweenpatientsgroupofbeforetherapyandcontrolgroup.Butnosignificantdifferencebetweenpatientsgroupofaftertherapyandcontrolgroup(P＞0.05).Conclusion:5Patientswithsomatizationdisorderhaveneurocognitivedysfunction,Buttheneurocognitivefunctionhave

8、improvedaftertherapy.〔Keywords〕Somatizationdisorder;Neurocognitivefunction;WisconsinCardSortingTest；Continuous