thickness variations within endothelial grafts for dsaek 厚度变化范围内的内皮移植角膜内皮移植术

thickness variations within endothelial grafts for dsaek 厚度变化范围内的内皮移植角膜内皮移植术

ID:14471850

大小:2.99 MB

页数:12页

时间:2018-07-28

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1、ThicknessvariationswithinendothelialgraftsforDSAEKsurgery.AspectraldomainanteriorsegmentOCTstudyAlbertoNeri,RosachiaraLeaci,PatriziaScaroni,ClaudioMacalusoOphthalmology,UniversityofParma,ItalyTheauthorshavenofinancialinterestinthesubjectmatterofthisposterDSAEKDescemetStrippingAutomatedEndothel

2、ialKeratoplastyCurrentlythestandardprocedureforendothelialpathology.Surgicalprocedure:DescemetstrippingInsertionoftheendothelialgraftAdesionwithairbubbleMicrokeratome(orfemtosecondlaser)cut:asportationofa300/350/400µmanteriorlamellaDonorbuttonharvesting:TrephinationThenormalcorneaisthickerinth

3、eperipheryandthinnerinthecenter.Tissueharvestingwithmicrokeratomeandfemtolaser,thatmeasurelamellarthicknessfromepithelialsurface,createsregularlamellaeforanteriorkeratoplastytechniques,buttheremainingendotheliallamellae,thataretheoneusedforDSAEK,necessarilychangeinthicknessfromcentertoperipher

4、y.Crosssectionalprofile=MeniscusPURPOSEToevaluatevariationsinthicknessofendothelialgraftsforDSAEKsurgerydependentonbotheccentricityandmeridianorientationusinghighresolutionanteriorsegmentOCT(CASIA®,Tomey,Japan).MATERIALSandMETHODS20eyesof20patientswhounderwentDSAEKsurgerywereexamined.Fullanter

5、iorsegmentscanswerecapturedwithCASIA®OCT.Theopticalcentreofthecorneaandeightmeridians(0°,45°,90°,135°,180°,225°,270°and315°)wereanalyzedwiththeFLAPTOOL,thatallowedpreciseidentificationandmeasurementofendothelialgraftthickness.Flapthicknesswasmeasuredatthecenterandat1,5mmand3mmeccentricityalong

6、eachmeridian.ANALYSISDATAforeachanalyzedeye(20):Centralflapthickness8thicknessvaluesat1.5mmeccentricity8thicknessvaluesat3mmeccentricityDescriptiveanalysisofthicknessvalueswasperformedforeacheccentricity.Todescribethevariationinthicknessatagiveneccentricity,theSDofthecorrespondingeightmeasurem

7、entswascalculatedineveryeye.Casia®FlapTool:MeasurementofTotalCornealThickness+FlapthicknessTheopticalcenterofthecorneaandeightmeridians(0°,45°,90°,135°,180°,225°,270°and315°)wereanalyzedwiththeFLAPTOOL,thatallowedpreciseidentificationan

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