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1、PopulationGeneticsvdxiaovdPopulationGeneticsAConciseGuideJohnH.vvvspieTHEJOHNSHOPKINSUNIVERSITYPRESSBaltimoreandLondon._./,.,.I.,.,_,_,,.,,......l,.,ll.”_.~....,.,.,.,,.*..I.....I...,.....,..I.......,..,’.,,’01998TheJohnsHopkineUniversityPressAllrightsreserved.Pub
2、lished1998PrintedintheUnitedStatesofAmericaonacid-freepaper9876543TheJohnsHopkinsUniversityPress2715NorthCharlesStreetBaltimore,Maryland21218-4363www.press.jhu.eduLibraryofCongressCataloging-in-PublicationDatawillbe'foundattheendofthisbook.Acatalogrecordforthisboo
3、kisavailablefromtheBritishLibrary.ISBN0-8018-5764-6ISBN0-8018-5755-4(pbk.)ToRobinGordonContentsListofFiguresixPrefacexi1TheHardy-WeinbergLaw11.1DNAvariationinDrosophila....................21.2Lociandalleles............................51.3Genotypeandallelefrequenci
4、es...................91.4Randomlymatingpopulations....................111.5Answerstoproblems.........................172GeneticDrift192.1Acomputersimulation........................202.2Thedecayofheterozygosity.....................222.3Mutationanddrift.............
5、.............272.4Theneutraltheory..........................322.5Effectivepopulationsize.......................352.6Thecoalescent............................382.7Binomialsampling..........................422.8Answerstoproblems.........................473NaturalSel
6、ection493.1Thefundamentalmodel.......................513.2Relativefitness............................523.3Threekindsofselection.......................553.4Mutation-selectionbalance.....................603.5Theheterozygouseffectsofalleles..................623.6Chan
7、gingenvironments.......................713.7Selectionanddrift..........................773.8Derivationofthefixationprobability................803.9Answerstoproblems.........................83vii.....I~,~-lI.,-_,.YI,IXOI*",.IIIY,'~I-,~"~~.'',~~,~I.................
8、.....................................x................................VlllContents4NonrandomMating854.1GeneralizedHardy-Weinberg....................864.
