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1、SpringerBriefsinStatisticsForfurthervolumes:http://www.springer.com/series/8921Hans-MichaelKaltenbachAConciseGuidetoStatistics123Dr.Hans-MichaelKaltenbachETHZurichSchwarzwaldallee2154002BaselSwitzerlande-mail:hans-michael.kaltenbach@bsse.ethz.chISSN2191-544Xe-IS
2、SN2191-5458ISBN978-3-642-23501-6e-ISBN978-3-642-23502-3DOI10.1007/978-3-642-23502-3SpringerHeidelbergDordrechtLondonNewYorkLibraryofCongressControlNumber:2011937427ÓHans-MichaelKaltenbach2012Thisworkissubjecttocopyright.Allrightsarereserved,whetherthewholeorpart
3、ofthematerialisconcerned,specificallytherightsoftranslation,reprinting,reuseofillustrations,recitation,broadcast-ing,reproductiononmicrofilmorinanyotherway,andstorageindatabanks.DuplicationofthispublicationorpartsthereofispermittedonlyundertheprovisionsoftheGerman
4、CopyrightLawofSeptember9,1965,initscurrentversion,andpermissionforusemustalwaysbeobtainedfromSpringer.ViolationsareliabletoprosecutionundertheGermanCopyrightLaw.Theuseofgeneraldescriptivenames,registerednames,trademarks,etc.inthispublicationdoesnotimply,eveninth
5、eabsenceofaspecificstatement,thatsuchnamesareexemptfromtherelevantprotectivelawsandregulationsandthereforefreeforgeneraluse.Coverdesign:eStudioCalamar,Berlin/FigueresPrintedonacid-freepaperSpringerispartofSpringerScience+BusinessMedia(www.springer.com)ToElkePrefa
6、ceThisbookowesitsexistencetothelecture‘‘StatisticsforSystemsBiology’’,whichItaughtinthefallsemester2010attheDepartmentforBiosystemsScienceandEngineeringoftheSwissFederalInstituteofTechnology(ETHZurich).Toalargepart,theaudienceconsistedofstudentswithbackgroundsin
7、biologicalsciences,whichexplainsthelargeproportionofbiologicalexamplesinthistext.Nevertheless,Ihopethatthistextwillbehelpfulforreaderswithverydifferentbackgroundswhoneedtoquantifyandanalyzedatatoanswerinterestingques-tions.Thisbookisnotintendedtobeamanual,norcan
8、itprovidetheanswertoallquestionsandproblemsthatonewillencounterwhenanalyzingdata.Boththebooktitleandthetitleofthebookseriesindicatethatspaceislimitedandthisbooktheref