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ID:11857325
大小:39.00 KB
页数:13页
时间:2018-07-14
《女性生殖道移行细胞癌及伴移行细胞癌分化肿瘤临床病理分析》由会员上传分享,免费在线阅读,更多相关内容在教育资源-天天文库。
1、女性生殖道移行细胞癌及伴移行细胞癌分化肿瘤临床病理分析作者:吕春燕1,杨开选2,陈鲜3,蔡建4单位:1.四川省成都中医药大学附属医院病理科,四川成都610072;2.四川大学华西第二医院,四川成都610000;3.四川省成都市363医院,四川成都610000;4.四川省成都市第九人民医院,四川成都610000【摘要】目的:分析女性生殖道移行细胞癌(transitionalcellcarcinoma,TCC)及伴移行细胞癌分化肿瘤的临床、病理及免疫组化表达特征,探讨TCC的诊断和鉴别诊断及细胞分化。方法:收集17例发生于女性生殖道的TCC及伴TCC分化肿瘤
2、的存档蜡块以及临床资料,对其进行临床病理形态学观察和免疫组化检测。结果:17例患者均为中老年人,肿瘤分别发生于卵巢12例,输卵管2例,子宫内膜2例,左卵巢转移至盆腔1例。临床症状主要为腹胀、腹痛、腹部包块,阴道流血等。随访时间6个月~4年3个月。健在7例,复发或转移2例,死亡4例,失访5例。大体表现为囊实性包块或实性包块,镜下见低级别尿路上皮癌改变,大多数TCC混合有其他组织学类型或为其他恶性肿瘤的伴随成分。免疫组织化学示15例作了CK7和CK20染色,15例均CK7阳性,CK20阴性。结论:女性生殖道的TCC及伴TCC分化肿瘤是女性生殖道恶性肿瘤的一种
3、少见类型,各个部位都可发生,但以卵巢最多见,均具有独特的病理特征,是一种预后较好的恶性肿瘤。【关键词】女性生殖道;移行细胞癌;临床病理分析ClinicopathologcalanalysisofprimarytransitionalcellcarcinomaoffemalegenitaltractandtumorwithtransitionalcelldifferentiationLVChun-yan1,YANGKai-xuan2,CHENXian3,etal(1.DepartmentofPathology,theAffiliatedHospitalof
4、ChengduUniversityofTCM,Chengdu610000,China;2.WestChinaSecondHospital,SichuanUniversity,Chengdu610072,China;3.No.363HospitalofChengduCity,Chengdu610000,China) Abstract:ObjectiveToexploretheclinicopathologcalandimmunohistochemistryexpressionfeaturesofprimarytransitionalcellcarcino
5、maoffemalegenitaltractandtumorwithtransitionalcelldifferentiation,andanalyzeitsdiagnosis,differentialdiagnosisandcytodifferentiation.MethodParaffinblockfilesandclinicaldataof17primarytransitionalcellcarcinomaoffemalegenitaltractwascollected.Thehistologicalfeaturesandimmunohistoch
6、emicalcharacteristicswereinvestigatedbylightmicroscopy.ResultsAllof17weremiddle-oldages,12locatedatovaries,2atfallopiantube,2atendometrium,and1atpelviccavitytransferedfromleftovary.Itsmajorclinicalsymptomsincludedabdominaldistension,painandlump,vaginalprofluviumsanguinis.Theywere
7、followed-upfor6monthsto4yearand3months,7wasaliveandwell,2ofrecrudescenceortransfusion,4diedand5lostfollow-up.Theywerecysti-solidlumporsolidlump.Theylookedlikelowgradeuroepitheliumcancer,mostmixedwithotherhistologytypeorbeaccompanimentwithmalignanttumorelse.Fifteenof17wasdetectedC
8、K7andCK20,allof15waspositiveinCK7,andall
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