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1、伽玛刀治疗脑胶质瘤（Gammakniferadiosurgeryforbrainglioma）Thedocumentisfromthenetwork,Icollectedandsortedout,ifthereareomissions,errors,butalsoaskmetocorrect!GammakniferadiosurgeryforbraingliomaGliomaisamalignantbraintumorderivedfromneuroepithelialtissue.Theincidencerateisbetween40and60%,andtheinciden
2、cerateis10/10/yearinadultsGliomaswereclassifiedandclassifiedaccordingtoWHO:Astrocytoma(1)astrocytoma(WHOgradeII)(2)anaplasticastrocytoma(WHOIII)(3)glioblastoma(WHOgradeIV)(4)astrocytomaofhaircelltype(WHOgradeI)(5)subependymalgiantcellastrocytoma(WHOgradeI)II,lessglioma(1)lowgradegliomas(WHO
3、grade1)(2)anaplasticoligodendroglioma(WHOIII)Ependymomaofthethirdcompartment(1)ependymoma(WHOgradeII)(2)anaplasticependymoma(WHOIII)(3)subependymalependymoma(WHOgradeI)Mixedglioma(1)astrocytoma(WHOgradeII)(2)anaplasticoligoastrocytoma(WHOIII)Choroidplexustumor(1)choroidplexuspapilloma(WHOgr
4、adeI)(2)choroidplexuscarcinoma(WHOgradeIII)EmbryonalneuroepithelialtumorMedulloblastoma(WHOgradeIV)VIIpinealtumorGliomagradeIandIIbelongtobenignstage,gradeIIIandgradeIVbelongtomalignantstage.GliomacanevolvefrombenignstagetomalignantstageinvarioustreatmentsduringthecourseofdiseaseThereisalwa
5、ystheproblemofrecurrenceanddiffusioninthetreatmentofmalignantglioma.Surgerycannotcompletelyremovethetumor,andradiotherapyalsohastheboundaryoftumordeterminationAlargenumberofnecroticcellsandhypoxiacellsareaccumulatedinthecenterofglioma,whichhasastrongresistancetoradiationGliomaproblemsurgery
6、orradiationtherapyistherealboundaryisnotclear,consistentwithedemaaroundthetumorthathavetumorcells,sosurgeryandradiotherapyareincapableofaction;anotherkindofunderstandingistumorcellscanobeythenervefibers,ortoglialstemcellsandtumorstemcellsspreadtootherpartsofintracranialInthisway,willbelinke
7、dtotheconventionalradiotherapyandchemotherapy,malignantgliomatoputirradiationdoserequirementisveryhigh,andonlyfromthetreatmentof1.5~2GY,thetreatmentprocessislong,ofteninthecourseoftreatmentoftumorrecurrenceisoutofcontrol,andthefunctionofreceiving6000cGY~
