【摘要】目的了解不孕妇女月经周期中β-内啡肽(β-EP)变化规律及其与生殖激素的关系,探讨不孕患者精神心理状"> 【摘要】目的了解不孕妇女月经周期中β-内啡肽(β-EP)变化规律及其与生殖激素的关系,探讨不孕患者精神心理状" />
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时间:2018-07-12
《不孕妇女β-内啡肽与生殖激素水平及其与精神心理因素关系的探讨》由会员上传分享,免费在线阅读,更多相关内容在教育资源-天天文库。
1、不孕妇女β-内啡肽与生殖激素水平及其与精神心理因素关系的探讨【关键词】不孕妇女【摘要】目的了解不孕妇女月经周期中β-内啡肽(β-EP)变化规律及其与生殖激素的关系,探讨不孕患者精神心理状况、体内β-内啡肽水平与生殖的相互关系。方法对19例不孕妇女进行心理状况评分,测定月经周期中不同时间β-内啡肽及生殖激素水平,同时进行排卵监测。结果(1)不孕组β-EP水平卵泡中期最低、围排卵期稍高、黄体中期显著升高,周期中呈上升趋势,并明显高于同龄妇女(P<0.05)。(2)不孕组黄体中期LH、E2、P显著降低,T显著升高(P<0.05);
2、周期中PRL水平均显著升高(P<0.01)。(3)卵泡中期β-EP与FSH、LH呈显著负相关,与E2呈显著正相关(P<0.01);围排卵期β-EP与LH呈显著负相关(P<0.05),与PRL呈显著正相关(P<0.01);黄体中期β-EP与PRL、P呈显著正相关(P<0.01)。(4)不孕组β-EP水平与心理状况评分呈显著正相关(P<0.001)。结论(1)正常及不孕妇女月经周期中血浆中β-EP的变化与生殖周期密切相关。(2)不孕妇女β-EP水平显著升高,是不孕的发生、发展中起一定作用。(3)不孕妇女β-EP水平显著升高并与心理状况评分呈显著正相关,提示心理治疗在不孕夫妇咨询和综
3、合治疗中起着不可忽视的作用。关键词不孕β-内啡肽生殖激素精神心理因素Astudyofregularchangeofβ-EPandreproductivehormonesinmenstrualcycleandthecorrelationbetweenβ-EPandpsychologicalfactorsininfertilewomen4、:24px"align=center>ZhangShaozhen,ChenXiaoyan,ChenZhiqinTheXinhuaHospitalofShanghaiSecondMedicalUniversity,Shanghai200092.【Abstract】ObjectiveTofindouttheregularchangeofβ-EPandreproductivehormonesinmenstrualcycleandthecorrelatio5、nbetweenβ-EPandpsychologicalfactorsininfertilewomen.Methods21casesofinfertilitywomˉen,thepsychologicalstatewerescored,theβ-endophinandotherreproductivehormonesatdifferentphasesweremeasured,andtheovulationmonitoredsimultraneously.Results(1)Theplasmalevelofβ-EPininfertilegroupandcontrolwerelow6、estinmid-follicularphase,elevatedalittleinperiovulatoryphaseandraisedsignificantlyinmid-lutealphase(P<0.05),displayingaascendingtrendincycles.Ininfertilegroupplasmaβ-EPweresignificantlyhigherinthreephasescomparedwithcontrolgroup(P<0.05,respectively).(2)Inthreephases,serumLH,E2andPweresignifi7、cantlylower,serumTwassignificantlyhigherthancontrolgroup(P<0.05,respectivelty).TheserumPRLlevelsofinfertilegroupweresignificantlyhigherthancontrolgroupinthreephases(P<0.001,respectively).(3)Ininfertilegroupthereweresignificantnegativecorrelationbet
4、:24px"align=center>ZhangShaozhen,ChenXiaoyan,ChenZhiqinTheXinhuaHospitalofShanghaiSecondMedicalUniversity,Shanghai200092.【Abstract】ObjectiveTofindouttheregularchangeofβ-EPandreproductivehormonesinmenstrualcycleandthecorrelatio
5、nbetweenβ-EPandpsychologicalfactorsininfertilewomen.Methods21casesofinfertilitywomˉen,thepsychologicalstatewerescored,theβ-endophinandotherreproductivehormonesatdifferentphasesweremeasured,andtheovulationmonitoredsimultraneously.Results(1)Theplasmalevelofβ-EPininfertilegroupandcontrolwerelow
6、estinmid-follicularphase,elevatedalittleinperiovulatoryphaseandraisedsignificantlyinmid-lutealphase(P<0.05),displayingaascendingtrendincycles.Ininfertilegroupplasmaβ-EPweresignificantlyhigherinthreephasescomparedwithcontrolgroup(P<0.05,respectively).(2)Inthreephases,serumLH,E2andPweresignifi
7、cantlylower,serumTwassignificantlyhigherthancontrolgroup(P<0.05,respectivelty).TheserumPRLlevelsofinfertilegroupweresignificantlyhigherthancontrolgroupinthreephases(P<0.001,respectively).(3)Ininfertilegroupthereweresignificantnegativecorrelationbet
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