gene therapy 基因治疗

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1、GeneTherapyGAC1ClarenceIntroductionWhatisagene?basicunitofheredityinalivingorganismWhatisgenetherapyhereditarydiseasesinsertionofgenes->individual'scells&tissuesadefectivemutantalleleisreplacedwithafunctionaloneHowitworks“normal”gene->patient’s“abnormal”onetargetcellsb

2、yavectorretrovirusesadenovirusesadeno-associatedvirusesherpessimplexvirusesDevelopment2003,UCLA,potentialtreatmentforParkinson’sdisease2006,NationalInstitutesofHealth,killerT-cellhelpedtreatcancer2007,MoorfieldsEyeHospitalandUniversityCollegeLondon’sInstituteofOphthalm

3、ology,firstgenetherapytrialforinheritedretinaldisease.DebateProsAdvancedtechnologyissupposedtobenefitmankindStretchmankind’slivesGlimmerofhopeRidinheriteddiseasesthatnormallytreatmentcannotbeavoidedConsEthicalReligiousMedicalReligiousReligiousMedicalConclusionHumanGeno

4、meProjectin2003OtheradvanceofscienceThegenetherapywillsucceedReferenceGeneTherapy(2008),ornl[online]Availableat:http://www.ornl.gov/sci/techresources/Human_Genome/medicine/genetherapy.shtml[Accessed4November2008]Genetherapy(2008),Wikipedia[online]Availableat:http://en.

5、wikipedia.org/wiki/Gene_therapy[Accessed4November2008]GeneTherapyforCancerQ&A(2008),NationalCancerInstitute[online]Availableat:http://www.cancer.gov/cancertopics/factsheet/Therapy/gene[Accessed3November2008]Humangenomeproject(2008),Wikipedia[online]Availableat:http://e

6、n.wikipedia.org/wiki/Human_genome_project[Accessed4November2008]TheEthicsofGeneTherapy(2008),ndsu[online]Availableat:http://www.ndsu.nodak.edu/instruct/mcclean/plsc431/students/bergeson.htm[Accessed4November2008]Weighingtheprosandconsofgenetherapy(2008),helium[online].

7、Availableat:http://www.helium.com/items/166289-weighing-the-pros-and-cons-of-gene-therapy[Accessed4November2008]Whataretheethicalissuessurroundinggenetherapy(2008),GeneticsHomeReference[online].Availableat:http://ghr.nlm.nih.gov/handbook/therapy/ethics[Accessed3Novembe

8、r2008]ReferenceDNA(2008),battlingforhealth[online].Availableat:http://cancer.battlingforhealth.com/wp-content/uploads