参麦注射液对改善急性创伤患者应激反应的临床研究

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1、参麦注射液对改善急性创伤患者应激反应的临床研究2O11年7月第49卷第20期?临床研究?参麦注射液对改善急性创伤患者应激反应的临床研究半冼建平李向东周莺田宗亮裘晓红(厂H市天河区中医医院,广东F-~)H510655)【摘要】目的探讨参麦注射液改善急性创伤患者应激反应的临床效果.方法60例急性创伤患者随机分为实验组和对照组,两组均给予常规治疗,实验组加用参麦注射液.另选择30例健康人作为空白组.检测伤后4h,24h,30d后Cor浓度和B—end浓度(空白组仅在30d后检测1次),30d后三组均进行Scl一90心理状

2、态评分.结果①实验组和对照组与空白组比较,Cor和B—end在伤后4h及24h内非常显着性升高(P<O.01),实验组与对照组比较,对照组24h升高程度更为显着(P<0.01);伤后30d实验组Scl一90与空白组无显着性差异(P>0.05),对照组SCL一90显着高于空白组和实验组(P<O.05o②Scl一90总分与24hCor浓度及24hB—end浓度均存在显着正相关(r=0.166,P<0.05;r=0.176,P<0.05).结论参麦注射液辅助治疗急性创伤患者,可以显着改

3、善患者心理状态,而且参麦注射液本身也有一定的治疗作用,值得临床应用推广.【关键词】参麦注射液;急性创伤;Cot;B—end;应激反应【中图分类号】R641【文献标识码】B【文章编号】1673—9701(2011)2O一35—02TheStressReactionofShenmaiInjectionforimprovingofPatientswithAcuteInjury.AClinicalStudyX~NjianpingLIXiangdongZHOUYinTIANZongliangOIuXAaohongGuangz

4、houMunicipalTianheDistrictTraditionalChineseMedicalHospital,Guangzhou510655,China【Abstract】ObjectiveToexploretheclinicaleffectofShenmaiinjectionforimprovingthestressreactionofpatientswithacuteinjuryMethodsSixtycasesofpatientswithacuteinjuryasstudiedobjectwerer

5、andomlydividedintoexperimentalgroupandcontrolgroup30casesineach.Bothgroupsweregivenroutinetherapy,andexperimentalgroupwereaddedwithShenmaiinjeetion30casesofhealthypeopleswereasblankgroup.CorandB-endweredetectedat4h,24hand30dafterinjury(blankgroupweredetectedon

6、lyonetimeafter30d),Scl-90ofthreegroupsweredetectedafter30d.Results①Experimentalgroupandcontrolgroupcomparedwithblankgroup,CorandB—endat4hand24hincreasedsignificantly(P<0.01);experimentalgroupcomparedwithcontrolgroup,theindexesat24hhadmoresignificantlyincrea

7、sing(P<0.O1);Scl-90betweenexperimentalgroupandblankgrouphadnosignificantdifference(P>0.05),Scl-90ofcontrolgroupwassignificantlyhigherthanexperimentalgroupandblankgroup(P<0.05).②CorandB-endhadat24hafterinjuryhadsignificantpositivecorrelationwithScl一90(

8、r=0.166,P<0.05;r=0.176,P<0.05).ConclusionShenmaiinjectionusedforadjuvanttherapyofacuteinjurycanturnthementalstatebettersignificantly,andithassometherapeuticaction,too,soitisa