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《针对不同疗程舌下含服粉尘螨滴剂治疗螨过敏变应性鼻炎伴哮喘患儿的疗效评价》由会员上传分享,免费在线阅读,更多相关内容在应用文档-天天文库。
1、针对不同疗程舌下含服粉尘螨滴剂治疗螨过敏变应性鼻炎伴哮喘患儿的疗效评价DOI:10.7504/nk2016010203屮图分类号:R587.1A目的:分析不同疗程舌K含服粉尘螨滴剂治疗螨过敏变应性鼻炎版哮喘患儿的临床疗效。方法:选取2013年1月-2016年1月120例螨过敏变应性鼻炎伴哮喘患儿,按照数字表法随机分为观察组与对照组,每组60例。观察组连续治疗3年,对照组连续用药1年。分别使用鼻炎症状评量表(TNSS评分)、鼻炎对症药物评量表(TRMS评分)、哮喘口间症状评量表(DASS评分)、哮喘夜间症状评量表(NASS评分)、
2、哮喘对症药物评分(TAMS评分)、视觉疼痛模拟量表(VAS评分)以及呼气峰流速(PEF)和不良反应发生率观察两组患者的临床疗效。结果:两组患者治疗前各指标相比无统计学意义,但观察组的临床疗效优于对照组(P<0.05);观察组仅有2例出现腹泻、皮疹等不良反应;对照组仅有3例出现腹泻、皮疹等不良反应,两组差异无统计学意义。结论:通过研究发现,3年为舌下含服粉尘螨滴剂治疗螨过敏变应性鼻炎版哮喘的最佳疗程,能够有效改善患儿的临床症状,具有较高的安全性,值得在临床屮推广应用。关键词:粉尘螨滴剂;螨过敏变应性鼻炎;哮喘Theeffectof
3、differenttreatmentofsublingualmiteallergyDermatophagoidesFarinaeDropstreatmentofallergicrhinitisandasthmaevaluationGAOMiaoping,HUANGYu-e,LIXiaoping,GUANBing-enDepartmentofPharmacy,TheThirdAffiliatedHospitalofGuangzhouUniversity,GuangdongGuangzhou510150[Abstract]:Obje
4、ctive:analysisofdifferentcoursesoftonguesublingualadministrationclinicalefficacyofimmunotherapywithDermatophagoidesFarinaeDropsinmiteallergicrhinitisversionoftheasthmachildren.Methods:120casesofallergicrhinitisandasthmawereselectedfromJanuary-2016,January2013,andwere
5、randomlydividedintotheobservationgroupandthecontrolgroup,60casesineachgroup.Observationgroupfor3yearsofcontinuoustreatment,controlgroupfor1consecutiveyears.Respectively,theuseofrhinitissymptomsratingscalescore(TNSS),rhinitissymptomsandmedicationRatingScalescore(TRMS)
6、,asthma,daytimesymptomratingscale(DASS)scoreandasthmanighttimesymptomratingscale(NASS)scoreandasthmadrugsforthesymptomaticscore(TAMs)score,painvisualanaloguescale(VAS)andpeakexpiratoryflow(PEF)andadversereactionsoccurrencerateoftheobservationtheclinicalefficacyofthet
7、wogroupsofpatients.Results:twogroupsofpatientsbeforeeachindexshowednostatisticalsignificance,buttheclinicalcurativeeffectofobservationgroupisbetterthancontrolgroup(P<0.05);intheobservationgroup,only2casesappeareddiarrhea,rashandotheradversereactions;inthecontrolgr
8、oup,only3casesofdiarrhea,rashandotheradversereactions,thedifferencebetweenthetwogroupsnostatisticalsignificance.Conclusion:throught