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时间:2020-05-14
《老年慢性心衰患者血尿酸和炎性因子水平变化及相关性.pdf》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、·648‘西南国防医药2015年6月第25卷第6期明比索洛尔未增加患者死亡风险。由此推测。随着betablockersforchronicobstructivepulmonarydisease:ameta—analysis[J].RespirMed,2003,97:1094—1101.治疗时间的延长,心功能逐渐改善,与常规组比较,SalpeterS,OrmistonT,SalpeterE.Cardioseleetivebeta—blockers死亡率应会出现下降趋势,故我们将继续随访,观forchro
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5、:invest,1994,93:2639—2648.arandomizedtrial[J].RespiratoryMedicine,2011,105:44-49.[81AhmedMI,AbanI,LioydSG.Arandomizedcontrolledphaseiibf3JNathanielMHawkins,Michae!RMacDonald,MarkCPetrie,ettrialofbeta(1)一receptorblockadeforchronicdegenerativemitrala1.Bis
6、oprololinpatientswithheartfailureandmoderatetoregurgitation[J].AmCollCardiol,2012,60:833—838.severechronicobstructivepulmonarydisease:arandomizedcontrolledtfial~].EuropeanJournalofHeartFailure,2009,11:(收稿日期:2015.02-09)684—690.[41SalpeterSR,OrmistonTM,Sa
7、lpeterEE,eta1.Cardioselective老年慢性心衰患者血尿酸和炎性因子水平变化及相关性庹田.张欣【摘要】目的探讨老年慢性心力衰竭(CHF)患者血尿酸水平和血清炎性因子水平的变化及相关性。方法选择60例老年CHF患者为研究组,其心功能分级(NYHA)lI级12例,Ⅲ级28例和Ⅳ级20例;另选择同期行健康体检的心功能正常老年人4O例为对照组,检测两组的血尿酸和血清炎性因子水平,并进行超声心动图检查。结果研究组血尿酸及IL.6、TNF-ct和hs—CRP水平均较对照组有显著升高(P<0.
8、05),且随着患者心功能恶化程度的加重,其各指标水平也相应增加;研究组左室舒张末期内径(LVEDD)较健康对照组显著增加,而左心室射血分数(LVEF)和左心室舒张早期血流峰值和舒张晚期血流峰值的比值(E/A)较健康对照组显著减少(P<0.05),且随着患者心功能恶化程度的加重,这些指标水平也相应地增加或减少;研究组血尿酸水平与白介素.6(IL-6)、肿瘤坏死因子.ct(TNF-ct)和超敏c反应蛋白(hs—CRP)水平均呈正相关(,:=0.60、0.75
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