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1、EditorialTheSARSCoronavirus:RapidDiagnosticsintheLimelightAsthesevereacuterespiratorysyndrome(SARS)epi-Tojudgetherealvalueofthistestandthereforetousedemicspreads,specific,rapid,andpracticaldiagnosticitoptimally,weneedmuchmoreinformation.Whataretestswillbecomeincreasinglyc
2、ritical,bothforthecontrolthebestspecimenstoobtainfrompatients?TheGermansoftheepidemicandforthemanagementofpatients.AtfoundthatsputumcontainedafarstrongerPCRsignalpresent,outsideEastandSoutheastAsiadiagnosisde-thanupperrespiratorytractsamples(5);Poonandhispendsonaclinicalc
3、asedefinitionthatincludestravelto,colleagues(2)testedonlynasopharyngealaspirates.Itorexposuretosickcontactswhohavetraveledto,specificcouldbethatifsputumhadbeenusedinstead,thepartsoftheworld(1).Astheepidemicmatures,however,sensitivityofthetestwouldhavebeencloserto100%.such
4、epidemiologicconnectionswillbeincreasinglydif-When,duringthecourseofillnessandinfection,doficulttodemonstrate,andaclinicalcasedefinitionthatsamplesbecomepositive?Whendotheybecomenega-dependsonthisinformationwillbecomeincreasinglytive?Whatisthedistributionofvirusinthebody?
5、Isitinirrelevant.InEastandSoutheastAsia,therapidlyex-theblood?When?Isitintheurine?Itappearstobepandingepidemicmakesspecificviraldiagnosisevenpresentinthestool,butthereisalmostnoinformationonmoreessential.Insuchanevolvingsituation,thereporteitherthequantityorthetiminganddu
6、rationofshed-byPoonetal.fromHongKong(2),incombinationwithding.thepublisheddiagnostictechnologiesofthatgroupandAPCR-baseddiagnostictestforaninfectiousdiseaseothersinEuropeandtheUnitedStates(3–5),takesonhasadvantagesanddisadvantages.Itcanbeexpectedtoextraordinaryimportance.
7、Moreover,thedevelopmentbeverysensitive.Itallowsaread-outinamatterofhours.andpublicationofarapidtestfortheSARScoronavirusinItalsohasthepotentialtobequantitative.Ontheotherclinicalsamples,justweeksafterthefirstreportsofthehand,itisexpensive,anditrequirestechnologyandemergen
8、ceofthedisease(6)isextraordinary.trainedtechnologistsoftennotavailableinthelocalityofAsahistoric
