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时间:2020-03-21
《氨基胍对脊髓损伤大鼠后肢运动功能的影响.pdf》由会员上传分享,免费在线阅读,更多相关内容在工程资料-天天文库。
1、中国实用神经疾病杂志2014年6月第17卷第1l期ChineseJournalofPracticalNervousDiseasesJun.2014,Vo1.17No.11·35·comeanalysisofabraintissueoxygendirectedtherapy[J].Jinmortality[J].JNeurotrauma,2010,27(7):13431353.Neurosurg,2009,111(4):672—82.[8]SpiottaAM,StiefelMF。GraciasVH,eta1.Braintis
2、sueoxy—E33StiefelMF。SpiottaA。GraciasVH,eta1.Reducedmortalitygen-directedmanagementandoutcomeinpatientswithsevererateinpatientswithseveretraumaticbraininjurytreatedwithtraumaticbraininjury[J].JNeurosurg,2010,113(3):571—braintissueoxygenmonitoring[J].JNeurosurg,2005
3、,103:580.805—811.[9]ChangJJ,YounTS,BensonD,eta1.Physiologic,functional[43WhiteH.VenkateshB.Cerebralperfusionpressureinneuro—outcomecorrelatesofbraintissuehypoxiaintraumaticbraintrauma:areview[J].AnesthAnalg,2008,107(3):979—988.injury[J].CritCareMed,2009,37(1):283—
4、290.[5]DaleyML,NarayananN,LefflerCW.Model—derivedassess[10]OddoM,LevineJM,MackenzieL,eta1.Brainhypoxiaisasso—mentofcerebr0vascu1arresistanceandcerebra1bloodflowfolciatedwithshort—termoutcomeafterseveretraumaticbrainlowingtraumaticbraininjury~J].ExpBiolMed(Maywood)
5、,injuryindependentofintracranialhypertensionandlowcere—2010,235(4):539545.bralperfusionpressure[J].Neurosurgery,201l,69(5):1037—[6]SteinSC,GeorgoffP,MeghanS,eta1.Relationshipofag—1045.gressivemonitoring,treatmenttoimprovedoutcomesinsevere[11]RohlwinkUK,ZwaneE,Fieg
6、genAG,eta1.Therelation—traumaticbraininjury[J].JNeurosurg,2010,112(5):1105—shipbetweenintracranialpressureandbrainoxygenationin1112.childrenwithseveretraumaticbraininjury[J].Neurosurger—[7]SteinSC,GeorgoffP,MeghanS,eta1.150yearsoftreatingy,2012,70(5):1220I230;1231
7、.severetraumaticbraininjury:asystematicreviewofprogress(收稿201310-25)氨基胍对脊髓损伤大鼠后肢运动功能的影响王磊尹忠民闻华陈实张可帅刘甲才董玉书解放军第463医院神经外科/全军精神外科治疗中心沈阳110042【摘要】目的研究大鼠脊髓损伤后氨基胍对其后肢运动功能的影响。方法选择62只体质量、活动力相似的大鼠制作大鼠脊髓压迫伤模型,根据随机数字表法分为观察组(氨基胍治疗组)31只及对照组(未治疗组)31只,比较2组大鼠后肢运动功能。结果观察组建模后24h一氧化氮
8、含量平均(0.851±0.0473)~mol/g·pro,一氧化氮合酶活性平均(0.269±0.0147)U/mg·pro,均明显低于对照组;建模后4周振幅测量平均(1.98±0.46)mV,潜伏期平均(8.91±0.88)ms,均显著低于对照组;BBB行为学评分(16.94-5.1)分,显著高于对照组
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