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1、滋阴益气活血解毒法治疗2型糖尿病合并脂肪肝临床观察摘要:日的:探讨滋阴益气活血解离法对2型糖尿病(T2DM)合并脂肪肝(NAFLD)患者空腹血糖、血脂、肝功能、肝脏影像学的影响。方法:将符合入选标准的60例患者随机分为对照组和治疗组,各为30例,均进行糖尿病常规治疗■饮食体质址控制、加强运动并使用口服降糖约物调节血糖。对照组服用肝旨清胶囊,治疗组服用肝旨清胶囊加用滋阴益气活血解毒组方中纱治疗。两组疗程均为5个月,评定治疗后的临床疗效。结果:两组病例治疗前各项检查指标比较无统计学意义(P>0.05);经治疗后,对照组和治疗组空腹血糖、餐后2h血糖、血脂、肝功能和脂肪肝等级与
2、治疗前比较,差异具有统计学意义(P<0.05或0.01),除空腹血糖外,治疗组各项检查指标优于对照组,差异具有统计学意义(P<0.05或0.01);治疗组总体疗效优于对照组,,差异具有统计学意义(Pv().()1)。结论:滋阴益气活血解毒法对2型糖尿病合并脂肪肝患者空腹血糖、血脂、肝功能均有改善作用。关键词:2型糖尿病合并脂肪肝;肝功能;滋阴益气活血解毒法StudyonclinicalefficacyofthemothodofZiyinYiqiHuoxueJieduimposedonthetype2mellituswithnon-alcoholicfattyliverZh
3、angqim,ChengXihua2,YuRong2(1.GraduateInstituteofEducation2010GraduateofHunanUniversityofTraditionalChineseMedicine,ChangSha410208;2.HunanUniversityofTraditionalChineseMedicine,SchoolofMedicine,ChangSha410208)Abstract:Objective:ToobservetheclinicalefficacyofthemothodofZiyinYiqiHuoxueJiedui
4、mposedonthetype2mellituswithnon-alcoholicfattyliver.Method:Teselected60patientswithtype2diabetesmellituswithnon-alcoholicfattyliverwhichwerediagnosedwithdeficiencyofbothyinandqi,turbidphlegmbloodstasisbyTCM・Thesepatientsweredividedintocontrolandtherapygroupsrandomly.Theyallperlormedbasict
5、reatment,likeoralantidiabeticdrugand,LiverpurposeQingCapsule,dietcontrolaswellasmoreexercisetoregulatethebloodglucoselevel,whilethepatientsoftherapygroup,inadditiontotheabovetreatment,weregiventheChinesemedicineofZiyinYiqiHuoxueJiedu•Thetreatmentperiodwas5months.Liverultrasoundexamination
6、andbiochemicaltests(thefastingbloodglucose,2hourpostprandialbloodglucose.includingbloodlipid,liverfunction)aswellasthetotaleffectwereearnedoutforthose60patientsbeforeandafterthetreatmeResult:Therewasnosignificantdifferencebetweenthefattyliverdegreeandbiochemicaltestsoftwogroupsbeforetreat
7、ment(P>().05)・After5months,thebloodglucose,2hourpostprandialfastingbloodglucose,thebloodlipid,liverfunctionandthefatlyliverdegreeofthetwogroupswereallimprovedtodifferentdegrees(P<().05,0.0I),“ndthoseofthetherapygroupexceptthefastingbloodglucoseimprovedmoresignifican