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1、不同MRI技术在诊断新生儿HIE中的应用研究吴继志武林顾维苏州大学附属儿童医院摘要：目的:分析不同MRI技术在诊断新生儿缺氧缺血性脑病(IIIE)屮的应用价值。方法:回顾性分析2015年7月勺17年2月我院收治的46例HIE患儿的临床资料,所有患儿入院后均完成常规MR1扫描、磁敏感加权成像(SW1)及弥散加权成像(DWI)扫描，分析不同MRI技术诊断新生儿HIE的临床价值。结果：(1)木组46例HIE患儿共检出病灶130枚，其中SWI扫描检出病灶数目最多(86.92%),其次为DWI序列(70.00%),常规MRI序列中以T2FLAIR序列
2、检出病灶数目最多(56.92%),HIE患儿病灶主要分布于大脑皮质区，其次为室鼓膜，DWI对大脑皮质损伤诊断阳性率高，SWI对小脑、鼓室膜、破膜下与破膜外损伤诊断阳性率较高。(2)46例HIE常规MRI检出阳性21例,DWI检出27例,SWI检出33例，DWI+SWI联合检出41例,以三者联合检查检出HIE阳性率最高(89.13%),其次为SWI序列(71.74%)。结论:MRI不同序列中以SWI对新生儿HIE诊断阳性率最高，其次为DW1序列，采用DWI联合SWI序列扫查可提高H1E早期检出率。关键词：新生儿缺氧缺血性脑病;MRT;磁敏感加
3、权成像;弥散加权成像;作者简介：吴继志，E-mail:wjz0346@163.com收稿日期：2017-08-30ApplicationofdifferentMRItechniquesinthediagnosisofneonataiHIEWuJi-zhiWuLinGuWeiChildren，sHospitalofSoochowUniversity;Abstract：ObjectiveToanalyzetheapplicationvalueofdifferentMRItechniquesinthediagnosisofneonatalhypo
4、xicischemicencephalopathy(HIE).MethodsTheclinicaldataof46casesofchildrenwithHTEtreatedinourhospitalfromJuly2015toJuly2017wereretrespectivelyanalyzed.AllchildrenwereexaminedroutineMRIscan,magneticsusccptibilityweightedimaging(SWI)anddiffusionweightedimaging(DW1)scan.Theclin
5、icalvalueofdifferentMRItechniquesinthediagnosisofneonatalHIEwasanalyzed.Results(1)Therewereatotalof130lesionsdetectedin46casesofchildrenwithHIE,andthenumberoflesionsdetectedbySWIscanningwasthelargest(86.92%),followedbyDWIsequence(70.00%)•AmongconventionalMR!sequences,thenu
6、mberoflesionsdetectedbyT2FLAIRwasthelargest(56.92%).Mostlesionsweredistributedinthecerebralcortex,thenventriculartympanicmembrane.ThepositiverateofDWIinthediagnosisofcerebralcortexinjurywashighwhilethepositiveratesofSWIinthediagnosisofcerebellum,tympanicmembrane,subduralan
7、depiduralinjurywerehigh.(2)Therewere21positivecasesdetectedbyconventionalMRI,27casesdetectedbyDWI,33casesbySWIand41casesbyDWI+SWTcombineddetection.TheposiliverateofcombineddetectionoftheabovethreeforHIEwasthehighest(89.13%),followedbySWIsequence(71.74%)・ConclusionThepositi
8、verateofSWIinMRIsequencesisthehighestinthediagnosisofneonatalHIE,followedbyDWIsequence.Th
