资源描述：
《Dynamics of vesicle slf-assembly and dissolution》由会员上传分享，免费在线阅读，更多相关内容在学术论文-天天文库。
1、THEJOURNALOFCHEMICALPHYSICS125,1649082006Dynamicsofvesicleself-assemblyanddissolutionabHiroshiNoguchiandGerhardGompperInstitutfürFestkörperforschung,ForschungszentrumJülich,52425Jülich,GermanyReceived9August2006;accepted7September2006;publishedo
2、nline27October2006Thedynamicsofmembranesisstudiedonthebasisofaparticle-basedmeshlesssurfacemodel,whichwasintroducedearlierPhys.Rev.E73,0219032006.ThemodeldescribesßuidmembraneswithbendingenergyandÑinthecaseofmembraneswithboundariesÑlinetension.T
3、heeffectsofhydrodynamicinteractionsareinvestigatedbycomparingBrowniandynamicswithaparticle-basedmesoscalesolventsimulationmultiparticlecollisiondynamics.Particlesself-assembleintovesiclesviadisk-shapedmembranepatches.Thetimeevolutionofassemblyisfou
4、ndtoconsistofthreesteps:particleassemblyintodiscoidalclusters,aggregationofclustersintolargermembranepatches,andÞnallyvesicleformation.ThetimedependenceoftheclusterdistributionandthemeanclustersizeisevaluatedandcomparedwiththepredictionsofSmoluchowsk
5、irateequations.Ontheotherhand,whenthelinetensionissuddenlydecreasedorthetemperatureisincreased,vesiclesdissolveviaporeformationinthemembrane.Hydrodynamicinteractionsarefoundtospeedupthedynamicsinbothcases.Furthermore,hydrodynamicsmakesvesiclemoresp
6、hericalinthemembrane-closureprocess.©2006AmericanInstituteofPhysics.DOI:10.1063/1.2358983I.INTRODUCTIONdynamicalbehaviorsinthelysisofliposomes:openingupbyporeformation,inside-outinversion,burst,andvesicleAmphiphilicmoleculessuchaslipidsanddetergent
7、sshrinkagewithoscillations.Pore-openingandruptureofformalargevarietyofmesoscopicstructures,suchasspheri-vesicleswerealsoobservedunderpositivesurfacetension1Ð3calandcylindricalmicelles,andbilayermembranes.Ininducedbyadhesiontoasurface,22opticalillumin
8、ation,22,23particular,bilayermembranesarebiologicallyimportantasormicropipetteaspiration.24Ð26modelsystemsfortheplasmamembraneandintracellularTheoreticalmodelsofbilayermembranescanbeclassi-compartmentsinlivingcells.Inthermalequilibrium,theÞedintotwog
