功能性消化不良危险因素对症状与预后的影响

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1、华中科技大学硕士学位论文TheimpactofriskfactorsoffunctionaldyspepsiaonsymptomsandprognosisMajor:GastroenterologyMasterdegreecandidate:JiangZhifengSupervisor:Pro.LiuShiAbstractBackgroundThereareafewreportsaboutfunctionaldyspepsia（FD）riskfactor，whichfocusedmoreontheoveralldis

2、easeriskfactorsthanriskfactorsonthesymptoms，andlessreportsaboutaffectofprognosisofriskfactors。OurresearchfocusedonFD-relatedriskfactorintheimpactonthesymptomsandprognosis。MethodOursurveyed130casesofout-patientswhichmeettheRomeIIIcriteria，examinatedexcludedstoma

3、chorganicdiseaseandothervisceralorganinvolvementbyendoscopicandultrasonographyandrefluxdisease。ConditionstoreceiveFDquestionnaire。Bylogisticregressionmodelsexaminetherelatedriskfactorsandfollow-uponeyear,observedtheoutcome。3华中科技大学硕士学位论文ResultsAdjustingforgender

4、,theOR（oddsratio）=2.77and3.09inpostprandialfullnessandearlysatiety，butthereare0.48and0.54inepigastricpainandepigastricburningrespectively。Adjustingforage，OR=1.02inepigastricpain，but0.95，0.98and0.96inpostprandialfullness，earlysatietyandepigastricburningrespectiv

5、ely。Adjustingforsmoking,OR=0.10，0.52inepigastricpainandepigastricburningrespectively。Adjustingfordringking，OR=1.01inepigastricpain，but0.22，0.22，0.77inpostprandialfullness，earlysatiety，andepigastricburningrespectively。AdjustingforHP.（Helicobacterpylori）Infection

6、，OR=0.66，0.66，0.93and0.71inpostprandialfullness，earlysatiety，epigastricpain，epigastricburningrespectively。Adjustingforlifesatisfaction，OR=1.88，3.41inearlysatiety，epigastricpainrespectively，but0.49inepigastricburning。Adjustingformoodswings，OR=1.01，1.30and1.04inp

7、ostprandialfullness，epigastricpainandepigastricburningrespectively，while0.69inearlysatiety。Adjustingforeducation，OR=1.38，1.69and1.12inpostprandialfullness，earlysatietyandepigastricburningrespectively，while0.83inepigastricpain。Inthedistributionofsymptomsofriskfa

8、ctors,earlysatietyismoresusceptibleinhighereducation，P=0.028，andthereisgreaterprobabilityofepigastricpaininmoodswings，P=0.004。Follow-uponeyear，therearenosignificantdifferenc