《蛔虫、钩虫、蛲虫》PPT课件

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1、IntroductiontotheHelminths蠕虫Helminthsmeansworms,multicellularorganisms.PhylumClassNemathelminthesNematoda(roundworm)线虫纲线形动物门PlatyhelminthesTremetoda(flatworms)吸虫纲扁形动物门Cestoda绦虫纲TheNematodes线虫Therearemany,manynematodes2006诺贝尔奖:ＲＮＡ干扰机制2002年诺贝尔奖：程序性细胞死亡C.ElegansMorphologyCylindrical,no

2、n-segmented,bilaterallysymmetricalandsexesseparatePseudocele原体腔(pseudocoelom)Thebodywall:cuticle角皮层hypodermis皮下层longitudinalmuscle肌层Holomyariantype(Whipworm)Polymyariantype(Ascarids)Meromyariantype(Hookworm)ThearrangementofthesomaticmusclesDigestivesystemMouthpharynxesophagusintesti

3、neanus咽管食管肠管肛门ReproductivesystemmalereproductivesystemTestisseminalvesicle睾丸储精囊vasdeferens输精管ejaculatoryduct射精管Mostfemalesusuallyhavetwoovaries，oviductsanduterus..ovary—oviduct—uterus.ovary—oviduct—uterus..卵巢输卵管子宫vulva-vagina阴门阴道nervoussystemConsistof:circumesophagealnervering咽管神经环a

4、nd2or4longitudinalnervetrunks神经干ExcretorysystemExcretoryporeisanterior.排泄孔Noflamecellsarepresent.lifecycleM1M2M3M4EggL1L2L3L4Adultlarva(male&female)KindsoflifecycleinnematodesAscarislumbricoidesTrichuristrichiuraEnterobiusvermicularisHookwormsIndirectlifecycle:intermediatehostisnece

5、ssaryTrichinellaspiralisFilariaDirectlifecycle:Intermediatehostisnotnecessary土源性线虫（肠道线虫）生物源性线虫Pathogenesis1)Larvae：(1)dermatitiscausedbycutaneousinvasionandsubcutaneousmigrationoflarva;(2)injurytoorgansortissuesbymigrationoflarvaeinthebody2)Adults：(1)injurytointestinalmucosacausedby

6、theparasiteslivingingastro-intestinalsystem(2)injurytolymphaticsystem,musclesornervoussystemcausedbytheparasiteslivingintissuesWhataboutEgg？INTESTINALHELMINTHSAscarislumbricoides(roundworm)似蚓蛔线虫Trichuristrichiura(whipworm)毛首鞭形线虫Enterobiusvermicularis(pinworm)蠕形住肠线虫Ancylostomaduodena

7、leandNecatoramericanus(hookworms)钩虫2004年第二次寄调Ascarislumbricoides(ascarids)Adultsliveinintestineofhuman,causeAscariasis(蛔虫病)；Humanistheonlydefinitivehostofthisparasite.>1billionworldwidetheinfectiverateinChina12.72%HookwormsFivespeciesofhookworms:Ancylostmaduodenale十二指肠钩口线虫Necatorame

8、ricanus美洲板口线虫Ancylo