Epi-LASIK术后高阶像差和视觉质量的临床分析

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1、天津医科大学硕士研究生学位论文阶像差RMS值(S4)与各对比度视力的相关性随对比度的降低而增加，与5％对比度视力的相关具有统计学意义(r=0．364，P=0．034)。其他各阶RMS值与各对比度视力的关联均无统计学意义(尸

2、提示低对比度视力是一检测屈光术后视功能较敏感的指标。3．术前，眩光状态时极低对比度下的视力明显低于无眩光状态，术后，有无眩光状态时各对比度下的视力差异均无统计学意义。提示角膜表层切削术后患者视觉质量受眩光影响较小。4．Epi．LASIK手术后，球差和球样像差(54)可明显降低低对比度下的视力。提示行波前像差引导的个体化Epi．LASIK手术时尽可能减少球差的产生，将会带来较好的视觉质量。关键词：机械法准分子激光上皮瓣下角膜磨镶术；准分子激光原位角膜磨镶术；高阶像差；近视：对比度视力：眩光IIl天津医科大学硕士研究生学位论文AbstractObjective：To

3、investigatechangesinocularhigherorderaberrationsandcontrastvisualacuity,andanalyzethecorrelationshipbetweenhigh-orderaberrationanddifferentcontrastvisualacuityinmyopiaafterepipolislaserinkeratomileusis．AndhopingtheresearchCanprovidemoreinstructionsforrefractivesurgeonstochoosemoreapp

4、ropriateoperation．Methods：Aprospectivestudy．Sectionlincluded34moderatemyopiapatients．31eyesof17patientshadEpi—LASIKand30eyesof17patients，LASIK．Bestcorrectedvisualacuity,uncorrectedvisualacuity,manifestrefractionandwavefrontaberrationsweremeasuredandanalyzedpreoperativelyand4-6monthsa

5、ftersurgery．Section2included35eyesof35subjects．ThepreoperativesphererefractionWas一3．00～一6．00D．andthecyclinderrefractionwasO～一1．50D．Ocularhigher-orderaberrationwasmeasuredundermesopicconditionusingtheHartman-shackwavefrontanalyzer,high(1oo％)，moderate(25％)，lowcontrast(10％)andverylowcon

6、trast(5％)visualacuitywithandwithoutglareweremeasuredusingMulti—FunctionVisualAcuityTesterunderthesameconditionpreoperativelyand4monthsaftersurgery．Results：’。1．ThereWasnostatisticallysignificantdifferenceforhigherorderaberrationsbetweenEpi—LASIKgroupandLASIKgrouppostoperativelyregardl

7、essofthepupilsize．2．Fora6-mmpupil，themeanchangesinRMSforthe5thorder(S5)andthe6thorder(86)weresignificantlysmallerinEpi-LASIKgroupthaninLASIKgroup(户一2．055，。2．049；p-=0．044，O．001，respectively)，andS5were0．026士0．036¨mand0．046士0．042“m，S6were0．020士0．019p,mand0．041士0．027pm．Secondsphericalabe

8、rration(co)w