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时间:2019-05-27
《中药联合贝那普利治疗糖尿病肾病临床疗效_葛静》由会员上传分享,免费在线阅读,更多相关内容在行业资料-天天文库。
1、辽宁中医杂志2014年第41卷第1期·113·DOI∶10.13192/j.issn.1000-1719.2014.01.049中药联合贝那普利治疗糖尿病肾病临床疗效1,2葛静(1.南京中医药大学,江苏南京210046;2.江苏省中医院,江苏南京210029)摘要:目的:探讨中药联合贝那普利治疗糖尿病肾病的临床效果。方法:选择该院收治的128例糖尿病肾病患者的临床资料,其中,观察组64例患者采用中药联合贝那普利治疗,而对照组64例患者采用贝那普利治疗,比较两组患者2的临床效果。结果:治疗后,观察组患者的总有效率为93.75%,明显高于
2、对照组患者,且差异具有统计学意义(χ=4.23,P<0.05),观察组患者的24hUMA、SCr、CCr等指标均较对照组患者出现了明显改善,组间比较,差异具有统计学意义(P<0.05),观察组与对照组患者的血糖指标和血压指标均较治疗前出现了明显的改善,且组内比较,差异具有统计学意义(P<0.05),两组不良反应发生率相当,差异无统计学意义。结论:金芪降糖片与西药联合治疗糖尿病肾病可明显改善患者的临床症状,有利于患者病情的恢复,值得临床应用。关键词:中药;贝那普利;糖尿病肾病;临床效果中图分类号:R697文献标志码:B文章编号:1000
3、-1719(2014)01-0113-03ClinicalAnalysisofTraditionalChineseMedicineCombinedwithBenazeprilforTreatmentofDiabeticNephropathy1,2GEJing(1.NanjingUniversityofChineseMedicine,Nanjing210046,Jiangsu,China;2.JiangsuProvincialHospitalofTCM,Nanjing210029,Jiangsu,China)Abstract:Objec
4、tive:ToexploretheclinicalefficacyoftraditionalChinesemedicinecombinedwithbenazeprilfortreatmentofdiabeticnephropathy.Methods:128caseswithdiabeticnephropathyinourhospitalweredividedintotwogroups,includingtheob-servationgroupof64caseswithtraditionalChinesemedicinecombined
5、withbenazepriltherapy,andthecontrolgroupof64pa-tientstreatedwithbenazepril.Results:Aftertreatment,theoveralleffectiverateofobservationgroupwas93.75%,significantly2higherthanthatofthecontrolpatients,andthedifferencewasstatisticallysignificant(χ=4.23,P<0.05),observationgr
6、oup's24hUMA,SCr,CCrotherindicatorshadsignificantimprovementthanthoseofthecontrolgroup,andthedifferencewasstatistical-lysignificant(P<0.05).Theobservationgroupandthecontrolgrouppatients'bloodsugarlevelandbloodpressuretargetshadimprovementthanthosebeforetreatment,andthedi
7、fferencewasstatisticallysignificant(P<0.05).Therewasaconsiderablein-cidenceofadversereactionsinbothgroups,andthedifferencewasnotstatisticallysignificant.Conclusion:TraditionalChinesemedicinecombinedwithbenazeprilfortreatmentofdiabeticnephropathycansignificantlyimproveth
8、etreatmentofdiabeticne-phropathy,anditisconducivetotherecoveryofthepatients'condition.Keywords:Chinesemedicine
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