补精益视片联合甲钴胺片治疗眼压控制后青光眼疗效观察_李翔

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1、辽宁中医杂志2014年第41卷第9期·1793··博导成果·DOI∶10．13192/j．issn．1000-1719．2014．09．001补精益视片联合甲钴胺片治疗眼压控制后青光眼疗效观察1221李翔，王桃，贺小张，肖西立(1．成都中医药大学附属医院眼科，四川成都610072;2．江西省萍乡市人民医院，江西萍乡337000)摘要:目的:观察补精益视片联合甲钴案片对眼压控制后青光眼患者视功能损害的疗效，并初步探索其作用机理。方法:严格按照纳入和排除标准，选取成都中医药大学附属医院(四川省中医院)眼科门诊眼压控制后青光眼患者60例，按就诊先后顺

2、序1∶1随机分为观察组与对照组，观察组给予补精益视片及甲钴胺片口服，对照组给予甲钴胺片口服，连续用药6个月，观察用药前后视力、视野、症状体征等指标的变化，评价用药疗效。结果:观察组西医疗效总有效率88.23%，对照组59.57%，差异有统计学意义(P＜0.01);观察组中医证候疗效总有效率86.21%，对照组57.14%，差异有统计学意义(P＜0.05);MS、MD、LV、视野计分治疗后与治疗前相比，观察组均有改善，差异有统计学意义(P＜0.05)，对照组无统计学意义(P＞0.05)。结论:补精益视片治疗眼压控制后青光眼疗效确切，可不同程度改善

3、患者中医症状，提高视力、视觉敏感度，有效控制视野缺损，从而保护青光眼患者视功能。关键词:青光眼;补精益视片;视功能保护;临床观察中图分类号:Ｒ755文献标志码:B文章编号:1000-1719(2014)09-1793-04ClinicalObservationofBujingYishiTabletCombinedMethecobalforGlaucomaofIOPunderControl1221LIXiang，WANGTao，HEXiaozhang，XIOAXili(1．DepartmentofOphthalmology，TeachingHos

4、pitalofChengduUniversityofTCM，Chengdu610072，Sichuan，China;2．DepartmentofOphthalmology，JiangxiPingxiangPeople'sHospital，Pingxiang337000，Jiangxi，China)Abstract:Objective:ToobservetheclinicaleffectofBujingYishiTabletcombinedMethecobalontheglaucomawhosein-traocularpressurewereco

5、ntrolled，andexplorethemechanismofitinitially．Methods:60patientswererecruitedfromoutpatientwithsameinclusionandexclusioncriteria．Theyweredividedinto2groupsas1:1proportionrandomly．ThetestgroupwastreatedwithBujingYishiTabletandMethecobalwhilethecontrolgrouptreatedwithMethecobal

6、．Bothgroupswereundergone6monthsofcontinuousmedication，observingsymptomsandsigns，eyesight，visualfieldbeforeandaftertreatmentrespectively．Ｒesults:Theto-taleffectiverateoftestgroupwas88．23%，andthatofcontrolgroupwas59．57%andtheeffectoftestgroupwasbetterthanthatofcontrolgroup(P＜0

7、．01)．ThetotaleffectiverateofTCMsymptomsscoresoftestgroupwas86．21%andthatofcontrolgroupwas57．14%andtheeffectoftestgroupwasbetterthanthatofcontrolgroup(P＜0．05)．Aftertreatment，theindexesincludingMS，MD，LVandvisualfielddefectscorewereimprovedsignificantlyintreatmentgroup(P＜0．05)．

8、Therewasnosignificantchangeincontrolgroup(P＞0．05);Conclusion:BujingYishiTab