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1、中国组织工程研究与临床康复第14卷第38期2010–09–17出版JournalofClinicalRehabilitativeTissueEngineeringResearchSeptember17,2010Vol.14,No.38www.CRTER.org五种不同血管支架材料学特点及置入后的生物相容性☆12熊杰,姜岩Materialcharacteristicsoffivedifferentvascularstentsandtheirbiocompatibilityafterimplantation12XiongJie,JiangYan
2、Abstract1OBJECTIVE:Toevaluatetheperformance,compatibilityandapplicationprospectsofbloodvesseltissueengineeredscaffolds.DepartmentofTraditionalChineseMETHODS:Using“tissueengineering,scaffoldmaterials,biocompatibility,performance,application”fortheChinesekeywordsMedicine,Aff
3、iliatedand“tissueengineering,intravascularstent,biocompatibility,performance,using”fortheEnglishkeywords,acomputersearchHospitalofMedicalwasperformedbetweenJanuary1993andOctober2009.ArticlesrelatedwiththebiomaterialsandtissueengineeringbloodCollegeofChinesePeople’sArmedves
4、selswereincluded;repeatedstudyorMetaanalysisarticleswereexcluded.Thereare26articlesmainlydiscussingthetypesPoliceForces,Tianjinandpropertiesoftissueengineeredvascularmaterials.300162,China;2DepartmentofRESULTS:Thenaturalscaffoldshavestrongaffinitywithcells,canprovideforcel
5、lgrowth,proliferation,differentiationandTraditionalChinesefunctioningwithsimilarextracellularmatrixscaffoldconditionasinvivodevelopment,thusaggregatingcellsintotissues,Medicine,Tianjincontrollingtissuestructure,andregulatingcellphenotype;immunerejectionisverylow,andcomplia
6、nceisgood.ButmechanicalCorpsHospitalofChinesePeople’sstrengthisrelativelypoor.Syntheticpolymerscaffoldhasprecisemaneuverability,butlacksbiologicalsignalsandfunctionalArmedPoliceForces,groupsinextracellularmatrix,andpoorlyadheretotheseedcells;andsomeacidmaterialsmaygenerate
7、inthedegradationTianjin300162,process,exhibitingsomelocaleffects;biologicalsignalsisabsent,andthescaffoldisnotsusceptiblebycellrecognition.InChinaaddition,thekeytoimprovethebiocompatibilityofstentsshouldbethebloodcompatibilityandhistocompatibility.XiongJie☆,StudyingCONCLUS
8、ION:Althoughsyntheticmaterialshavebecometheresearchhotspot,butthecompatibilityafterimplan