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ID:32891038
大小:2.06 MB
页数:26页
时间:2019-02-17
《年轻人急性心肌梗死的危险因素及聚集状况》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、温州医学院硕士学位论文年轻人急性心肌梗死的危险因素及聚集状况姓名:王雅洁申请学位级别:硕士专业:内科学指导教师:施陈刚2012-05-21温州医学院硕士学位论文年轻人急性心肌梗死的危险因素及聚集状况中文摘要目的随着生活方式的改变,工作节奏加快,近年来年轻人急性心肌梗死(AMI)发病率逐年增多,而发病年龄却呈年轻化趋势,AMI是冠状动脉粥样硬化性心脏病(简称冠心病)致命的表现方式,虽然年轻人心肌梗死在住院与出院存活率方面高于老年人心肌梗死,但年轻人心肌梗死对社会和家庭的影响较大,长期生存率低,而且心肌梗死后如不能有效控制危险因素,患者致死率和致残率相应增加。目前大多数研究是以中老年人为对象,
2、而对年轻人AMI患者的研究较少。本研究主要观察年轻人急性心肌梗死的危险因素及聚集状况,分析这些因素与年轻人急性心肌梗死的关系,为早期防治提供依据。方法:选择2006年至2011年期间入住我院年轻AMI患者(年龄≤45岁)共70例作为疾病组,并以同期入院年龄相匹配的154例正常患者(冠状动脉造影结果显示为正常)作为对照组,分析冠心病传统危险因素高血压、糖尿病、高血脂状况、肥胖、吸烟史及早发冠心病家族史(PCHD)在两组问的变化及聚集状况,并初步探讨C反应蛋白(CRP)对AMI影响。结果:(1)疾病组总胆固醇水平(Tc)、甘油三酯(TG)、CRP值、吸烟和早发冠心病家族史的比率明显高于对照组(
3、结果分别5.18±1.38vs4.41±1.01mmol/L、3.97+1.24vs3.05±1.01mmol/L、20.86+5.10vs3.77±1.65mg/L、71.43%vs57.14%、22.86%vsl2.86%)(P<0.05),而高血压、糖尿病、肥胖、高密度脂蛋白胆固醇(HDL—C)、低密度脂蛋白胆固醇(LDL.C)在两组间比较无统计学意义。(2)疾病组与对照组相比,有危险因素者明显增多(95.71%vs78.57%)(尸4、30%)(尸5、ngpeopleisincreased.Althoughthesurvivalrateofyoungpeopleishigherthantheelderly,theyoungpatientshavealargerinfluencetothefamilyandsociety.Therateofpatient’Smortalityandmorbiditywillincreaseiftheycannoteffectivelycontroltheriskfactors.Thestudiesaremainlyabouttheelderlyforthemonent,wedidnotknowmuchab6、outtheyoungone.Thepurposeofthisstudywastoinvestigatetheclusteringstatusofacutemyocardialinfarction(AMI)riskfactorsinyoungmenandtoanalysetherelationshipofriskfactorswithAMI.MethodsSeventyyoungpatientswithAMIagedunder45andonehundredandriftv.fourage.matchednon.AMIpatientsascontrolwereenrolledbetween27、006and2011.Traditionalriskfactors(smoking,hypertension,hyperlipidemia,diabetes,obesity,familyhistory)andtheirplasmalevelsofC—reactiveprotein(CRP)wereevaluated.Results(1)ThelevelsofTotalcholesterol(TC)、Triglycerid
4、30%)(尸5、ngpeopleisincreased.Althoughthesurvivalrateofyoungpeopleishigherthantheelderly,theyoungpatientshavealargerinfluencetothefamilyandsociety.Therateofpatient’Smortalityandmorbiditywillincreaseiftheycannoteffectivelycontroltheriskfactors.Thestudiesaremainlyabouttheelderlyforthemonent,wedidnotknowmuchab6、outtheyoungone.Thepurposeofthisstudywastoinvestigatetheclusteringstatusofacutemyocardialinfarction(AMI)riskfactorsinyoungmenandtoanalysetherelationshipofriskfactorswithAMI.MethodsSeventyyoungpatientswithAMIagedunder45andonehundredandriftv.fourage.matchednon.AMIpatientsascontrolwereenrolledbetween27、006and2011.Traditionalriskfactors(smoking,hypertension,hyperlipidemia,diabetes,obesity,familyhistory)andtheirplasmalevelsofC—reactiveprotein(CRP)wereevaluated.Results(1)ThelevelsofTotalcholesterol(TC)、Triglycerid
5、ngpeopleisincreased.Althoughthesurvivalrateofyoungpeopleishigherthantheelderly,theyoungpatientshavealargerinfluencetothefamilyandsociety.Therateofpatient’Smortalityandmorbiditywillincreaseiftheycannoteffectivelycontroltheriskfactors.Thestudiesaremainlyabouttheelderlyforthemonent,wedidnotknowmuchab
6、outtheyoungone.Thepurposeofthisstudywastoinvestigatetheclusteringstatusofacutemyocardialinfarction(AMI)riskfactorsinyoungmenandtoanalysetherelationshipofriskfactorswithAMI.MethodsSeventyyoungpatientswithAMIagedunder45andonehundredandriftv.fourage.matchednon.AMIpatientsascontrolwereenrolledbetween2
7、006and2011.Traditionalriskfactors(smoking,hypertension,hyperlipidemia,diabetes,obesity,familyhistory)andtheirplasmalevelsofC—reactiveprotein(CRP)wereevaluated.Results(1)ThelevelsofTotalcholesterol(TC)、Triglycerid
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