肌层浸润性膀胱癌治疗现状的临床荟萃

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1、授予单位代码10089学号或申请号20153267中国图书分类号R699.5HebeiMedicalUniversity硕士学位论文专业学位肌层浸润性膀胱癌治疗现状的临床荟萃研究生：张登所导师：黎玮教授专业：外科学二级学院：河北医科大学第二医院2018年3月河北医科大目录中文摘要··········································································································1英文摘要············································

2、······························································2英文缩写··········································································································4综述肌层浸润性膀胱癌治疗现状的临床荟萃··········································5致谢·························································

3、·························································22个人简历··········································································································23中文摘要肌层浸润性膀胱癌治疗现状的临床荟萃摘要目的：学习和了解肌层浸润性膀胱癌的各种治疗方法，对其治疗现状进行系统性的总结和分析。方法：通过查找相关书籍和文献，总结和分析肌层浸润性膀胱癌不同治疗方法的优缺点。结果：在其外科治疗方面，腹腔镜下根治性全

4、膀胱切除术已被广泛接受；随着医疗水平的进步，通过综合治疗来实现保留膀胱的治疗方式也是可行的；机器人辅助腹腔镜下根治性全膀胱切除术在未来将成为一个重要的发展方向；在条件适当的情况下，女性保留生殖器的手术方式也取得了较好的效果。以及随着新辅助治疗及分子靶向治疗的发展，在未来也将会有重要的突破。结论：根治性膀胱全切除术加盆腔淋巴结清扫一向都是肌层浸润性膀胱癌的标准治疗方案；腹腔镜下根治性全膀胱切除术的优点不仅在于它围手术期的病死率低，而且患者术后的生活质量也得到改善；机器人辅助腹腔镜下根治性全膀胱切除术的优点是手术创伤小、出血量少且恢复快，缺点在于其价格昂贵；在选择合适患者的情况下，女性保

5、留生殖器手术方式也取得了较好的效果；综合治疗保留膀胱的方式主要有辅助放化疗、分子靶向治疗、膀胱部分切除等方法，但仍需进一步探讨。关键词：肌层浸润性膀胱癌，现状，综合治疗，新辅助化疗，分子靶向治疗1英文摘要ClinicalstudyonthetreatmentofmuscleinvasivebladdercancerABSTRACTObjective:Learnandunderstandvarioustherapeuticmethodsofmuscleinvasivebladdercancer,andsystematicallysummarizeandanalyzethecurrent

6、treatmentstatus.Methods:Throughthesearchforrelatedbooksandliterature,theadvantagesanddisadvantagesofdifferenttreatmentsformuscleinvasivebladdercancerweresummarizedandanalyzed.Result:Initssurgicaltreatment,laparoscopicradicalcystectomyhasbeenwidelyaccepted;asthemedicallevelprogresses,itisalsofea

7、sibletoachievebladderpreservationtreatmentthroughcomprehensivetreatment;Robot-assistedlaparoscopicradicalbladderResectioninthefuturewillbeco-meanimportantdirectionofdevelopment;underproperconditions,femalegenitalsurgeryalsoachieve