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时间:2018-10-25
《根除幽门螺旋杆菌与不同亚型老年功能性消化不良疗效的关系》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、根除幽门螺旋杆菌与不同亚型老年功能性消化不良疗效的关系 [摘要]目的:分析根除幽门螺旋杆菌(Helicobacterpylori,HP)与不同亚型老年功能性消化不良(Functionaldyspepsia,FD)??效的关系。方法:2013年6月―2015年6月收治184例HP阳性老年FD患者,按照随机数字表法分为抗HP组、常规组各92例。均予FD常规治疗,抗HP组加用HP根除治疗,观察抗HP组HP根除成功情况,比较不同亚型患者治疗1个月后、治疗1年后疗效及复发情况。结果:抗HP组治疗1个月后、治疗1年后FD治疗总有效率分别为78.26%
2、、72.83%,均高于常规组的59.78%、57.61%;HP根除成功组治疗1个月后、治疗1年后总有效率分别为95.24%、98.21%,均高于HP根除失败组的68.42%、46.15%;抗HP组EPS亚型患者治疗1个月后、治疗1年后总有效率分别为86.00%、80.00%,均高于PDS亚型的69.05%、64.29%,差异有统计学意义(P0.05)。结论:根除HP可提高EPS型老年PD患者临床疗效。 [关键词]幽门螺旋杆菌;老年;功能性消化不良;疗效 中图分类号:R573.6文献标识码:A文章编号:2095-5200(2017)01-
3、077-03 DOI:10.11876/mimt201701031 RelationshipbetweeneradicationofHelicobacterpylorianddifferentsubtypesoffunctionaldyspepsiainelderlypatientsZHANGYue,ZHONGYuan.(DepartmentofGeriatrics,ShanghaiNo.6People’sHospital,Shanghai200233China) [Abstract]Objective:Thisstudyobject
4、ivewastoanalyzetherelationshipbetweeneradicationofHelicobacterpylori(HP)anddifferentsubtypesoffunctionaldyspepsia(FD)inelderlypatients.Methods:184elderlyHP-positiveFDpatientsadmittedinourhospitalfromJune2013toJune2015,weredividedintoanti-HPgroupandroutinegroup(n=92)bythera
5、ndomnumbertable.AllpatientsweregivenconventionaltreatmentofFD,anti-HPgroupwastreatedwithHPeradication,andtheeradicationofHPinanti-HPgroupwasobserved,andthecurativeeffectandrecurrenceofpatientswithdifferentsubtypeswerecomparedbetween1monthaftertreatmentand1yearaftertreatmen
6、t.Results:ThetotaleffectiverateofFD1monthaftertreatmentand1yearaftertreatmentwere78.26%and72.83%,respectively,whichwerebothhigherthan59.78%and57.61%intheroutinegroup;thetotaleffectiverateoftheanti-HPgroup1monthaftertreatmentand1yearaftertreatmentwere95.24%and98.21%,respect
7、ively,werebothhigherthan68.42%and46.15%oftheroutinegroup;thetotaleffectiverateofsubtypeofEPSpatientsinanti-HPgroup1monthsaftertreatmentand1yearaftertreatmentwere86.00%and80.00%,whichwerehigherthan69.05%and64.29%ofsubtypeofPDSpatientsinanti-HPgroup,thedifferencewasstatistic
8、allysignificant(P0.05).Conclusions:EradicationofHPcanimprovetheclinicalefficacyofelderlyP
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