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ID:18364808
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时间:2018-09-16
《甲壳素类神经导管修复周围神经的研究与进展》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、万方数据中国组织工程研究与临床康复第f3眷第47期2009—11—19出版JournalofOlinicalRehabilitativeTissueEngmeeringResearchNovember19,2009VoL13,No.47综述甲壳素类神经导管修复周围神经的研究与进展★张万里1,王伟2ProgressofchitinnerveconduitinperipheralnerverepairZhangWan~li,WangWei2Abstract0BJECTlVE:Tosummarizetheprogressonthebiomaterialsofchit
2、innerveconduittorepairperipheralnerveinjuryInrecentyears.DATASOURCES:Acomputer-basedonlinesearchofliteraturesrelatedtotheapplicationofthebiomaterialsofnerveconduitonperipheralnerveinjurywasperformedinMedlineandSpringerlinkbyusingthekeywordsof。nerveconduit。peripheralnerveinjury”betwe
3、enJanuary2000andAugust2009andthelanguagewaslimitedtoEnglish.Meanwhile.wesearchedChinaPeriodicalsFull-te)(tDatabaseandWeipudatabasefortherelatedChinesearticlespublishedbetweenJanuary2000andAugust2009withthesamekeywordsjnChinese.STUDYSELECTl0N:Inclusivecriteria:Researchesaboutthenon—b
4、iodegradablematerials.biodegradablematerialsandbiologicalderivativematerialsthatwererelatedtotheperipheralnerveinjurywereincluded.Exclusivecriteria:Theirrelevantandrepeatedarticleswereexcluded.MAlNOUTCOMEMEASURES:Nervetissueengineering,chitinnerveconduit,andpreparationofnerveconduit
5、.RESULTS:WiththeprogressofmedicaImaterials.theneuraltubeofnatureIorsyntheticmaterialsusedtobridgedefectoftheneuralinnervetissueengineeringscaffoldmaterialwithaguideandtopromotenerveregeneration.Inthebiodegradablematerial,chitinneuraltubecouldbedegradedwithinareasonableperiodoftime,b
6、iologicalcontrolcompatibility,performancedegradation,mechanicalpropertiesandporosity.Andinthestructureoftheconduit,combinedotherbiodegradablematerials。su内cemodification,addingseedcellsandnervegrowthfactor,andotheraspectsoftheexperimentalstudywereinvestigated.Changingthespatialstruct
7、ureofrenewableandmicro-environmentaimedtospeeduptherateofnervegrowth,andpromotetheresumptionofthegoodnervefunction.Andmaterial’ssurfacehadtobemodifiedandimprovedforconduittoadaptnerveduringthenerveregeneration.CONCLUSl0N:Withthecontinueddevelopmentofbiotechniqueandcross-correlationt
8、echnique,thebiomate
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