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ID:1771231
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时间:2017-11-13
《医药学临床医学毕业论文 术中输入乳酸钠林格液与醋酸钠林格液对血乳酸盐及酸碱平衡影响的研究》由会员上传分享,免费在线阅读,更多相关内容在学术论文-天天文库。
1、湖南师范大学本科毕业论文考籍号:XXXXXXXXX姓名:XXX专业:医药学临床医学论文题目:术中输入乳酸钠林格液与醋酸钠林格液对血乳酸盐及酸碱平衡影响的研究指导老师:XXX二〇一一年十二月十日【摘要】目的比较术中输入乳酸钠林格液和醋酸钠林格液血乳酸盐及血气的变化。方法40例择期手术患者按随机数字表随机分为乳酸钠组(L组)和醋酸钠组(A组),每组各20例,采用静吸复合全身麻醉。L组术中输入乳酸钠林格液,A组术中输入醋酸钠林格液,两组术中不交叉输入其他晶体液,输入胶体液均为菲克血隆(内含聚明胶肽)。观察诱导前,诱导后1h、2h、3h及4h的血乳酸盐、SpO2、PETCO
2、2、呼末异氟醚浓度、呼末N2O浓度、MAC及血气变化。结果两组在年龄、性别、身高、体重、ASA分级、手术时间、麻醉时间、术中输液量、出血量、尿量等方面均差异无显著性(P0.05)。乳酸盐正常值为0.50~2.22mmol/L。两组诱导前、诱导后1h、2h、3h、4h的血乳酸盐、SpO2、PETCO2、呼末异氟醚浓度、呼末N2O浓度、MAC等观察指标,组间比较P0.05(P=0.011),组内诱导后1hSpO2、乳酸盐与诱导前比较P0.05(P=0.000),组内诱导后4hMAC、呼末异氟醚浓度、呼末N2O浓度与诱导后3h比较,P0.05。两组诱导前、诱导后1h、2h
3、、3h、4h的血气变化,组间比较P0.05(P=0.040),组内诱导后2hpH与诱导后1h,比较P0.05(P=0.015),组内诱导后3hpH与诱导后2h,比较P0.05(P=0.015)。结论与术中输入醋酸钠林格液相比,输入乳酸钠林格液的病人有一过性血乳酸盐值升高及血pH值偏低现象。【关键词】乳酸钠;醋酸钠;脊柱手术;全身麻醉Thestudyoftheeffecttothebloodlactateandtheacid-basebalancewhengiventhelactatedRingersandacetatedsodiumsolutionduringthe
4、operation【Abstract】ObjectiveTOcomparethedifferentchangesofbloodlactateandbloodgaseswhengiventhelactatedRinger’ssolutionandacetatedsodiumsolutionduringoperation.Methods40patientsaredividedequallyintothelactatedRinger’sgroup(groupL)andtheacetatedsodiumgroup(groupA)randomly,adaptingthecom
5、binedintravenousandinhalationgeneralanesthesia.ThelactatedRinger’sgisgiveningroupLandtheacetatedsodiumingroupA.Neithergroupsarecross-givenothercrystalsolutionduringoperation,polygelineistheonlycolloidsolutioninbothgroups.Observethechangesofbloodlactate,SpO2,PETCO2,theendexpiratoryconce
6、ntrationofisofluraneandN2O,MACandbloodgasesbeforetheinductionandat1h,2h,3hand4hafterinduction.ResultsThereisnostatisticsdifference(P0.05)intheage,sex,stature,weight,ASAgrade,operationtime,anesthesiatime,thevolumeoftransfusionduringoperation,hemorrhageandurinevolumeetcofbothgroups.Theno
7、rmalvalueoflactateis0.50~2.22mmol/L.Theobservationindexofbloodlactate,SpO2,PETCO2,theendexpiratoryconcentrationofisofluraneandN2O,MAC,comparisonbetweengroups:P0.05(P=0.011);comparisonofSpO2,lactatebetween1hafterinductionandbeforeinductioningroups:P0.05(P=0.000);comparisonofMAC,endexp
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