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《ⅱ型糖尿病患者血清胰岛素浓度与血糖、糖化血红蛋白、c肽及血压、血脂的相关性研究》由会员上传分享，免费在线阅读，更多相关内容在工程资料-天天文库。
1、Ⅱ型糖尿病患者血清胰岛素浓度与血糖、糖化血红蛋白、C肽及血压、血脂的相关性研究关心1，赵玉红1，平静2，王晓蕾1，李坚1，卢熠1，吴丽霞1.1沈阳医学院沈洲医院,沈阳110002；2沈阳药科大学药学院,沈阳110016RELEVANCESTUDIESOFSERUMINSULINCONCENTRATION,BLOODGLUCOSEANDGLYCOSYLATEDHEMOGLOBINTHEINTYPE2DIABETESPATINTSGuanxin1,Zhaoyuhong1,Pingjing2,Wangxiaolei1,lijian1,Luyi1,Wulixia11Shenzho
2、uHospitalaffiliatedShenyangMedicalCollege,Shenyang110002;2ShenyangPharmaceuticalUniversity,Shenyang110016[Abstract]Objective:Tostudyfastingbloodglucose(FBG),glycosylatedhemoglobin(HbAlc),andinsulin(Ins)concentrations3indicatorsofmutualrelationsinpatientswithtype2diabetesandtheclinicalappl
3、ication.Method:FBG,HbAle,InsconcentrationswereRespectivelydeterminedbyenzymaticoxidation,immunizationturbidity,chemiluminescence.Aftertreatmentofthediabeticpatients1monthand2months,wereexamined.Results:type2diabetesintheFBG,HbAlc,Insweresignificantlyhigherthanthenormalcontrolgroup(P<0.01)
4、.Conclusion:GlucosemetabolismtargetandInslevelrelations:inimpairedglucosetolerance(IGT)totheclinicalearlytime,hasbeeninexistenceInsresistance,therelativelackofInscancompensatoryincreaseintheFBGtomaintainthenormallimitlevel;Clinicalearlytomid-FBGincreased,Insresistancegradualincrease,theIn
5、slevelrelativeinsufficiencyhastensobviously,β-cellfunctionappearsfromstrengthenstotheweakentransformation,inbloodInslevelswereunstablestateoffluctuation,isintheearlierdecompensatedperiod;Theclinicalmidandlatestage,appearscontinueshighFBG,theseriousInsresistancestillexisted,startstopresent
6、theInstobeabsolutelyinsufficient,Betacellfunctionisinadecompensatedperiodorthefailuretime,thebloodinsulinlevelreducesunceasingly.Theentirediabetescourse,thetypicalInsconcentrationcurvewasinvertedU-shapedapproximately.AsFBG,HBAIc,andInsreflectsthethreedifferentperiodsofFBGlevel,toprovidear
7、ecentclinicalvertical,theentireprocessofFBGlevelofinformationtoguideclinicaldevelopmentoftreatmentprogrammes.Keywords:Diabetes;Glycosylatedhemoglobin;Insulin;Hypertensin[摘要]目的探讨Ⅱ型糖尿病患者血糖(FBG)、糖化血红蛋白(HbAlc)、胰岛素(Insulin)、C肽（CPE）测定指标之间相互关系的临床应用，同时研究了与血压、血脂的相关性。方法选择Ⅱ型糖尿
