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1、2011.06.19李端、黄璐、袁碧芬、杨迪元、金颖康医生： 国际输血和血液学杂志编辑部送来几篇指南让我们编译，其中一篇是关于成人及儿童血小板增多症的，现组织你们翻译，请于7月15日前将翻译稿发回给我，再由我修改、审核。希望通过编译，有助于你们对血小板增多症的认识，并提高编译水平。由于我出差在外，没有你们的邮箱，所以请何映谊医生代为转发此邮件给你们，望见谅。谢谢！叶铁真成人及儿童血小板增多症诊疗指南Guidelineforinvestigationandmanagementofadultsandchildrenpresentingwithathrombocytosis李端从
2、这里开始。ClaireN.Harrison,1DavidBareford,2NaumanButt,3PeterCampbell,4EibhleanConneally,5MarkDrummond,6WendyErber,7TamaraEverington,8AnthonyR.Green,9GeorginaW.Hall,10BeverleyJ.Hunt,1ChristopherA.Ludlam,11RichardMurrin,12CatherineNelson-Piercy,1DeeptiH.Radia,1JohnT.Reilly,13JonVanderWalt,1BridgetWilk
3、ins1andMaryF.McMullin14Writinggroup:BritishCommitteeforStandardsinHaematologyKeywords:essentialthrombocythaemia,myeloproliferativedisorder,myelofibrosis,MDS.IntroductionTheguidelinegroupwasselectedtoberepresentativeofUkbasedmedicalexperts.MEDLINEandEMBASEweresearchedsystematicallyforpublication
4、sinEnglishfrom1966untilOctober2009usingavarietyofkeywords.ThewritinggroupproducedthedraftguidelinewhichwassubsequentlyrevisedbyconsensusbymembersoftheHaemostasisandThrombosisandHaemato-oncologyTaskForcesoftheBritishCommitteeforStandardsinHaematology.Theguidelinewasthenreviewedbyasoundingboardof
5、approximately50UKhaematologists,theBritishCommitteeforStandardsinHaematology(BCSH)andtheBritishSocietyforHaematologyCommitteeandcommentsincorporatedwhereappropriate.CriteriausedtoquotelevelsandgradesofevidenceareasoutlinedintheProcedureforGuidelinesCommissionedbytheBCSH(TableI).Theobjectiveofth
6、isguidelineistoprovidehealthcareprofessionalswithclearguidanceontheinvestigationandmanagementofthrombocytosisinbothadultandpaediatricpatients.Theguidancemaynotbeappropriatetoallpatientswiththrombocytosisandinallcasesindividualpatientcircumstancesmaydictateanalternativeapproach.TableI.Evidencest
7、atementsandgradesofrecommendations.ClassificationofevidencelevelsIa:Evidenceobtainedfrommeta-analysisofrandomizedcontrolledtrialsIb:EvidenceobtainedfromatleastonerandomizedcontrolledtrialIIa:Evidenceobtainedfromatleastonewell-desi
