中枢神经感染患者脑脊液免疫指标探讨

《中枢神经感染患者脑脊液免疫指标探讨》由会员上传分享，免费在线阅读，更多相关内容在应用文档-天天文库。

1、中枢神经感染患者脑脊液免疫指标探讨黄翔李罗清(岳阳市一人民医院湖南岳阳414000)目的：探究检测中枢祌经感染患者的脑脊液免疫指标的临床价值及意义。方法：从我院2013年09月〜2015年09月间收治的中枢神经感染患者中抽取66例，将其中确诊为病毒性脑膜炎的22例患者编入研究A组，确诊为结核性脑膜炎的22例患者编入研宄B组，确诊为化脓性脑膜炎的22例患者编入研究C组，另从同期健康体检人群中选取22例作为对照组。观察并比较各组的脑脊液CRP水平、NSE和IFN-γ的含量。结果：研究B组、研究C组的脑脊液CRP含量要明显高于对照组，其对比差异具有统计学意义(P&

2、lt;0.05)。研究A组、研究B组、研究C组的NSE均要显著地高于对照组，其对比具有显著的差异性，有统计学意义(P<0.05);同时，研究A、B组的IFN-γ含量明显要高于对照组，组间对比差异显著，具备统计学意义(P<0.05)。结论：在中枢祌经感染临床诊断鉴别工作中，观察脑脊液CRP水平、NSE和IFN-γ的含量有助于提高诊断的准确性，测定NSE指标有助于准确判断脑损害的程度，值得临床采纳。【关键词】中枢祌经感染；脑脊液；免疫指标；检测价值R741A1007-8231(2015)16-0134-02Immuneindexesofc

3、erebrospinalfluidinpatientswithcentralnervoussysteminfectionHuangXiangLiLuoqing.Apeople'sHospitalofYueyangCity,414000,China【Abstract】ObjectiveToexplorethedetectionofcerebrospinalfluidimmuneindexesofcentralnervoussysteminfectionpatientsclinicalvalueandsignificance.MethodsFromsep2013tosep2

4、015werepatientswithcentralnervoussysteminfectionof66cases,ofthemdiagnosedwith22patientsofviralmeningitisinstudygroupA,thediagnosisoftuberculousmeningitisin22patientsintothestudygroupB,diagnosedwithpurulentmeningitisof22patientsinstudygroupC,theotherfromthesameperiodhealthcheck-upcrowdfro

5、m22casesascontrolgroup.ObservationandcomparisonbetweengroupsofcerebrospinalfluidlevelsofCRPandNSEandthecontentofIFN-gamma.ResultsThestudygroupBandgroupCcerebrospinalfluidCRPlevelsweresignificantlyhigherthanthatofcontrolgroup,thecontrastdifferencesstatisticallysignificant(P<0.05).Resea

6、rchingroupA,groupBandgroupCofNSEweresignificantlyhigherthanthatofcontrolgroup,thecontrasthassignificantdifferences,withstatisticalsignificance(P<0.05);AandBatthesametime,theresearchgroupofIFN-gammalevelssignificantlyhigherthanthatofcontrolgroup,comparethesignificantdifferencebetweengr

7、oups,withstatisticalsignificance(P<0.05).ConclusionsInclinicaldiagnosisofcentralnervoussysteminfectiontoidentifywork,observethecerebrospinalfluidlevelsofCRPandNSEandthecontentofIFN-gammahelpstoimprovetheaccuracyofdiagnosis,determinationofNSEindicatorshelptoaccuratelyde