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1、小儿定喘口服液佐治支气管哮喘患儿的肺功能及临床疗效观察（济宁医学院附属医院儿科山东济宁272000）目的：探讨小儿定喘门服液治疗对支气管哮喘患儿肺功能的影响及临床疗效。方法：选取120例临床初诊为支气管哮喘的患儿，随机分为治疗组和观察组，各60例；（对照组给予西药口服治疗，治疗组在对照组的基础上联合小儿定喘门服液治疗）观察患儿咳嗽、痰量、喘息和喘鸣音等临床症状并评分；采用MIR型肺功能仪分别在治疗前后对其行肺功能测定，比较两组患儿治疗后2周的肺功能参数的变化。结果：治疗后两组患儿咳嗽、痰量、喘息及哮鸣音
2、临床症状评分均有显著性改善，治疗组显效36例，占60.0%;有效17例，占28.3%;无效7例，占11.7%;总有效率为88.3%。对照组显效24例，占40.0%;有效13例，占21.7%;无效23例，占38.3%;总有效率为61.7%。两组相比，治疗组的显效率、总有效率均明显高于对照组（P值分别<0.01,<0.05）o两组患儿治疗2周后用力肺活量（FVC）、一秒钟用力呼气量（FEV1）、最大呼气流量（PEF）、最大呼气屮期流速（FEF25-75）,得到显著性改善，与治疗前相比，四个指标数值均有明显提
3、升，两组相比，治疗组优于对照组，差异均有统计学意义（P<0.05）o结论：两种治疗方案均能改善小儿哮喘，但治疗组效果更优，说明小儿定喘门服液具有改善支气管哮喘患儿临床症状及肺功能的作用。关键词：小儿哮喘；哮喘；肺功能；临床疗效TheresearchofthepulmonaryfunctionandclinicaleffectofXiao-erding-chuanoralliquidofchildrenwithbronchialasthmaAbstract:objectivetoinvestigat
4、ethelungfunctionandclinicalcurativeeffectofXiao-erding-chuanoralliquidofinchildrenwithbronchialasthma。Methods120casesofclinicalfirstdiagnosisforchildrenwithbronchialasthmawerechoosed,andrandomlydividedintotreatmentgroupandobservationgroup;Therewere60case
5、sintwogroupsRespectively;ThetreatmentgroupwasgivenXiao-erding-chuanoralliquidonthebasisoftreatmentwiththeobservationgroup.Childrencough,sputumvolume,pantingandwheezingandotherclinicalsymptomswereobservedandscored;ThelungfunctionoftwogroupsweremeasuredUsi
6、ngMIRtypelungfunctionmeterbeforeandafter2weekofthetreatment,respectively;Thechangesinlungfunctionparameters.Werecompared.Results,Cough,sputumvolume,breathingandwheezingsoundclinicalsymptomscoresoftwogroupsweresignificantlyimprovedaftertreatment.36cases(6
7、0.0%)hadmarkedeffectofthetreatmentgroup;Effective17cases(28.3%),Invalid7cases(11.7%),Thetotaleffectiveratewas88.3%.24cases(40.0%)weremarkedlyimprovedofthecontrolgroup,;Effective13cases(21.7%),Invalid23cases(38.3%),Thetotaleffectiveratewas61.7%.Thesignifi
8、cantefficiencyandtotaleffectiverateintreatmentgroupweresignificantlyhigherthancontrolgroup(respectivelyPvalues<0.01,<0.05).Forcedvitalcapacity(FVC),forcedexpiratoryvolumeinonesecond(FEV1),maximumexpiratoryflow(PEF),t
