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1、四十八、基因研究领域的斗争Itwasthebiggestscientificgrudgematchsincethespacerace.TheGenomeWarshadeverything:twogroupswithappealingleadersreadytofightinascientificdeadheat,pushingthelimitsoftechnologyandrhetoricastheybattledtobecomethefirsttoreadeverylastoneofthe3billionDNA“letters”
2、inthehumanbody.Thescientificimportanceoftheworkisunquestionable.ThecompletedDNAsequenceisexpectedtogivescientistsunprecedentedinsightsintotheworkingsofthehumanbody,revolutionizingmedicineandbiology.Buttheraceitself,betweenthegovernment’sHumanGenomeProjectandRockville,
3、Md.,biotechnologycompanyCeleraGenomics,wasatleastpartlysymbolic,thepublic/privateconflictplayedoutinageneticlab.Nowtheraceisover.Afteryearsofpublicattacksandseveralfailedattemptsatreconciliation,thetwosidesaretakingasteptowardaperiodofcalm.HGPheadFrancisCollins(andAri
4、PatrinosoftheDepartmentofEnergy,animportantallyonthegovernmentside)andCraigVenter,thefounderofCelera,agreedtoholdajointpressconferenceinWashingtonthisMondaytodeclarethattheracewasover(sortof),thatbothsideshadwon(kindof)andthatthehostilitieswereresolved(forthetimebeing
5、).Nooneisexactlysurehowthingswillbedifferentnow.Neithersidewillbeturningoffitssequencingmachinesanytimesoon—the“finishlines”eachhascrossedarelargelyarbitrarypoints,“firstdrafts”ratherthanthedefinitiveversion.AndwhilethejointannouncementbringstheformerGenomeWarriorsclo
6、sertogetherthanthey’rebeeninyears,insiderssaythatfutureagreementsaremorelikelytotaketheformofcoordination,ratherthanoutrightcollaboration.Theconflictblewup,thisFebruarywhenBritain’sWellcomeTrust,anHGPparticipant,releasedaconfidentiallettertoCeleraoutliningtheHGP’scomp
7、laints.Ventercalledthemove“alowlifethingtodo.”Butbyspring,therewerethefirstsignsofathaw.“Theattacksandnastinessarebadforscienceandourinvestors,”VentertoldNewsweekinMarch,“andfightingbackisprobablynothelpful.”Atacancermeetingearlierthismonth,VenterandCollinspraisedeach
8、other’sapproaches,andexpressedhopethatallofthescientistsinvolvedinsequencingthehumangenomewouldbeabletosharethecredit.Bylate