蛇胆苦柏爽肤洗液治疗阴囊湿疹疗效及安全性评价

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1、蛇胆苦柏爽肤洗液治疗阴囊湿疹疗效及安全性评价新乡医学院第一附属医院皮肤科赵香容专家讲座[摘要]目的!观察5%蛇胆苦柏爽肤洗液治疗阴囊湿疹的疗效及安全性方法!将152例阴囊湿疹患者随机分为3组治疗组51例予5%蛇胆苦柏爽肤洗液外用对照A组50例予5%蛇胆苦柏爽肤洗液的单纯基质外用对照B组51例予曲安奈德益康哇乳膏外用每日2次井每周递减外用次数3周后观察疗效井评价其安全性结果!治疗组治愈率有效率与对照B组比较差异无统计学意义P>0.05两组疗效相当治疗组对照B组治愈率有效率与对照A组比较差异有统计学意义P<0

2、.053组比较对照B组起效时间较短观察3周结束时各组不良反应发生情况比较差异无统计学意义P>0.05随访显示治疗组复发率较低P<0.05结论!5%蛇胆苦柏爽肤洗液治疗阴囊湿疹疗效与曲安奈德益康哇乳膏相当优于5%蛇胆苦柏爽肤洗液的单纯基质长期使用复发率低不良反应较少Evaluationofefficacyandsafetyof5%butylflufenamateointmentintreatingscrotaleczemaWANGYan-yunLIZhan-guoCHENYan-huiSHITian-wei

3、ZHANGMinDepartmentofDermatologythePeopleSHoSpitalofZhengzhouZhengzhou450003China[abstract]Objective:ToevaIuatetheefficacyandsafetyofbutyIfIufenamateointmentintreatingscrotaIeczema.Methods:Onehundredandfifty-twopatientswithscrotaIeczemawererandomIydividedi

4、ntothreegroups:treatmentgroupandcontroIsA,B.51patientsintreatedgrouphadtaken5%butyIfIufenamateointment.50patientsincontroIAweregivenbutyIfIufenamateointmentbase.TriamcinoIoneacetonideandeconazoIecreamwasgivento51patientsincontroIB.AIIcreamswereappIiedtwic

5、edaiIyforthreeweeksandappIicationfreguencygraduaIIyreducedduringthetreatment.Results:TherewasnodifferenceincurerateandeffectiveratebetweentreatedgroupandcontroIB(P>0.05).ThecurerateandeffectiverateincontroIAdifferedsignificantIyfrombothtreatedgroupandcont

6、roIB(P<0.05).TreatmentwithtriamcinoIoneacetonideandeconazoIecreamshowedeffectsoonerthanwithothertwocreams.Nodifferenceinadverseeffectswasobservedamongthreegroups.FoIIow-upshowedIowerrecurrencerateingrouptreatedwith5%butyIfIufenamateointment.Conclusions:5%

7、butyIfIufenamateointmentandtriamcinoIoneacetonideandeconazoIecreamhavecomparativeeffectivenesswithfeweradverseeffectsandIowerrecurrencerateintreatingscrotaIeczema.[keywords]scrotaIeczema;butyIfIufenamateointment;econazoIecream;base[JCIinDelmatOI2013426377

8、-379]年,平均病程1916.1)周对照A组:50例,年龄17.5~69岁,平均年龄39.1112.9)岁,病程1周~8年,平均病程1819.7)周对照B组:51例,年龄17~67岁,平均年龄39.6111.4)岁,病程1周~9年,平均病程2117.3)周患者病情严重度参照湿疹面积及严重度指数评分法治疗组为10.6115.24)分,对照A组11.0914.23)分,对照B组10.8014.61)分3组患者的年龄病程及病情严重