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1、719PROPAMOCARB(148)FirstdraftpreparedbyEloisaDutraCaldas,UniversityofBrasilia,Brasilia,BRAZILEXPLANATIONPropamocarbhydrochlorideisacarbamatefungicidewithspecificactivityagainstOomycetespeciesthatcauseseed,seedling,root,footandstemrotsandfoliardiseasesinanumberofediblecrop
2、s.ThecompoundwasevaluatedbytheJMPRin1984,1986,1987and2005,whenanADIof0–0.4mg/kgbwandanARfDof2mg/kgbwwereestablished.Atthe37thSessionoftheCCPRitwasscheduledforresidueevaluation,withintheperiodicreviewprogramme,bythe2006JMPR.Themanufacturersubmitteddataonmetabolisminanimala
3、ndplants,degradationinsoil,residuesinsucceedingcrops;GAP,analyticalmethodsandprocessingstudies.Residuetrialssubmittedwereconductedonpotato,radish,onion,lettuce,spinach,cabbage,cauliflower,chicory,sweetpepper,tomatoes,summersquash,cantloupeandmelon.GAPinformationandresidue
4、trialsresultsonlettuce,cucumberandgingerwereprovidedbytheGovernmentofJapan.IDENTITYCommonname:PropamocarbhydrochlorideChemicalname:IUPAC:Propyl3-(dimethylamino)propylcarbamatehydrochlorideCAS:Propyl[3-(dimethylamino)propyl]carbamatehydrochlorideCASnumber:25606-41-1CIPACnu
5、mber:399EECnumber:245-125-9Molecularformula:C9H21ClN202Molecularmass:224.7g/molStructuralformula:CH3NNHOHCCH33OxHClPHYSICALANDCHEMICALPROPERTIESAdetailedchemicalandphysicalcharacterisationoftheactiveingredientisgivenbelow.PropertyResultsReferenceReportNo.ColourandodourCre
6、amcolouredstickycrystalswithtypical(Sixl/Rexer,1998;C001715/C001717;carbamateodour/whiteopaquecrystallinesoftWalkeretal.,1995;722/013)liquidwithweak,sicklysweetodourMeltingpoint64.2°C(Lehne,1990;A89312)Relativedensity1.051g/cm³at20°C/1.15g/cm³at20.5+0.5°C(Bittner/Rexer,C0
7、03480.MuehlbergerandLemke,2004;C044109.Walkeretal.,1995;722/013)-5-3Vapourpressure3.8x10/1.4x10Paat20°C(Miklautz,1990;A85057;Howarthetal.,-5-3(extrapolated)8.1x10/1.7x10Paat25°C1995;722/015)-41.6x10Paat30°C720PropamocarbPropertyResultsReferenceReportNo.-93VolatilityHenry'
8、slawconstantat20°C:8.50x10Pam(Renaud,2005;C046819)(calculated)mol-1Solubilityinwaterat>900g/Latp
