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1、AppliedBioinformaticsP.M.Selzer•R.J.Marhöfer•A.RohwerAppliedBioinformaticsAnIntroductionWith69Figures,61incolorand6TablesProf.PaulM.Selzer,Ph.D.AndreasRohwer,Ph.D.IntervetInnovationGmbHIntervetInnovationGmbHBioChemInformaticsBioChemInformaticsZurPropsteiZurPropstei55270Schw
2、abenheim55270SchwabenheimGermanyGermanypaul.selzer@intervet.comandreas.rohwer@intervet.comRichardJ.Marhöfer,Ph.D.IntervetInnovationGmbHBioChemInformaticsZurPropstei55270SchwabenheimGermanyrichard.marhoefer@intervet.comTranslators:PDFrankSeeber,Ph.D.ConorCaffrey,Ph.D.Dept.Bi
3、ology/ParasitologyDirectorofBiochemistryandMolecularParasitologyPhilippsUniversityMarburgSandlerCenterforBasicResearchinParasiticDiseasesKarl-von-Frisch-Str.8ByersHallN50835042MarburgUniversityofCalifornia,SanFranciscoGermany17004thStreetseeber@staff.uni-marburg.deSanFranci
4、sco,CA94158-2330USAcaffrey@cgl.ucsf.eduISBN:978-3-540-72799-6e-ISBN:978-3-540-72800-9LibraryofCongressControlNumber:2007937094©2008Springer-VerlagBerlinHeidelbergFirstpublishedinGermanunderthetitle:AngewandteBioinformatik2004Thisworkissubjecttocopyright.Allrightsarereserved
5、,whetherthewholeorpartofthematerialisconcerned,specificallytherightsoftranslation,reprinting,reuseofillustrations,recitation,broadcasting,reproductiononmicrofilmorinanyotherway,andstorageindatabanks.Duplicationofthispublicationorpartsthereofispermittedonlyundertheprovisionsof
6、theGermanCopyrightLawofSeptember9,1965,initscurrentversion,andpermissionforusemustalwaysbeobtainedfromSpringer.ViolationsareliabletoprosecutionundertheGermanCopyrightLaw.Theuseofgeneraldescriptivenames,registerednames,trademarks,etc.inthispublicationdoesnotimply,evenintheab
7、senceofaspecificstatement,thatsuchnamesareexemptfromtherelevantprotectivelawsandregulationsandthereforefreeforgeneraluse.Coverdesign:WMXDesignGmbH,Heidelberg,GermanyPrintedonacid-freepaper543210springer.comPrefaceThougharelativelyyoungdiscipline,bioinformaticsisfindingincreas
8、ingimportanceinmanylifesciencedisciplines,includ-ingbiology,biochemistry,medicine,
