资源描述：
《drug addictionfrom basic research to therapy外语英文电子书》由会员上传分享，免费在线阅读，更多相关内容在教育资源-天天文库。
1、DrugAddictionFromBasicResearchtoTherapyRaoS.Rapaka•WolfgangSadéeEditorsDrugAddictionFromBasicResearchtoTherapyEditorsDr.RaoS.RapakaDr.WolfgangSadéeNationalInstituteonDrugAbuseCollegeofMedicineandPublicHealthBethesda,MDOhioStateUniversityUSAColumbus,OHUSA
2、ISBN:978-0-387-76677-5e-ISBN:978-0-387-76678-2DOI:10.1007/978-0-387-76678-2LibraryofCongressControlNumber:2008926485©2008AmericanAssociationofPharmaceuticalScientistsAllrightsreserved.Thisworkmaynotbetranslatedorcopiedinwholeorinpartwithoutthewrittenperm
3、issionofthepublisher(SpringerScience+BusinessMedia,LLC,233SpringStreet,NewYork,NY10013,USA),exceptforbriefexcerptsinconnectionwithreviewsorscholarlyanalysis.Useinconnectionwithanyformofinformationstorageandretrieval,electronicadaptation,computersoftware,
4、orbysimilarordissimilarmethodologynowknownorhereafterdevelopedisforbidden.Theuseinthispublicationoftradenames,trademarks,servicemarks,andsimilarterms,eveniftheyarenotidentifiedassuch,isnottobetakenasanexpressionofopinionastowhetherornottheyaresubjecttopr
5、oprietaryrights.Printedonacid-freepaper987654321springer.comPrefaceThisbookaffordsacomprehensiveoverviewofcurrentresearchondrugaddictionandrelateddisciplines,withtopicalreviewswrittenbyeminentscientistsinthefield.ItwasinspiredbyajointAAPS–NIDAsymposium“F
6、rontiersinScience:DrugAddiction–FromBasicResearchtoTherapies”,heldinSeptember2004,attheNIHcampus.Subsequently,wehaveinvitedleadingscientiststocontributechaptersonabroadrangeoftopics,coveringbasicresearch(e.g.mechanismsofactionofdrugsofabuse,developmentof
7、receptor-specificligands,animalmodels),discoveryanddevelopmentoftherapies,andotherclinicalapplications.Asneuronalcircuitsinvolvedindrugaddictionalsoimpingeuponmanyothervitalfunctionsofthebrainandperipheraltissues,wehavebroadenedthescopetoincludepathophys
8、iologiesrelatedtodrugabuse/addiction.Forexample,thecomplexactionsofopioidsonpain,addictionliability,andotheradverseeffectshavetriggeredanintensivesearchfornon-addictiveopioidpainmedicationsandfornon-opioidanalgesicsdirecte
