dr. david brownstein iodine for thyroid & health.a holistic approach.american nutrition association. 3外语英文电子书

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1、CholesterolandIodine•1918,researchersdemonstratedthatfeedingiodinetorabbitscouldpreventthedepositionofcholesterolinarteriesofrabbitsthatwerefedcholesterol.Trans.Jpn.Path.8:221-4,1918.•Thesestudieswerereproducedandsimilarresultsreportedintheliteraturefourtimes.Arch.Exp.Pathol.Pharmokol.159:265-274,19

2、31Z.Gesamte.Exp.Med.87:683-702,1933J.Exp.Med.58:115-25,1933Res.Commun.Chem.Pathol.Pharmacol.1:169-184,1970CAD:AnUnderlyingMechanism(1)•Researcherslookedatthedevelopmentofatherosclerosisinrabbits•Controlgroup:Rabbitsfedhighcholesteroldiet•Treatmentgroup:Rabbitsfedhighcholesteroldietandtreatedwith:•T4

3、•Desiccatedthyroid•IodineCAD:AnUnderlyingMechanism(2)•Controlrabbitsfedcholesteroldevelopedmarkedaorticatherosclerosis•Rabbitsfedcholesterol-richdietandT4showedslighttomoderateaorticatherosclerosis•Rabbitsfedcholesterol-richdietandeitherdesiccatedthyroidoriodineshowedanabsenceThisstudyshowedthatiodi

4、nehasanofatheroscleroticlesionsindependentpositivebenefitinacholesterol-richdietaswellasasynergisticeffectwithdesiccatedthyroidhormone.J.Exp.Med.58:115-25,1933IodineandCholesterolLevels•136Subjects•Iodineintakeandlipidparameters•Comparedtoiodinesufficient,non-goiterouscontrols,iodine-deficientgoiter

5、oussubjects:SignificantlyhigheraveragecholesterollevelsandLDLcholesterollevels.Klin.Pediat.208:123-8.1996Iodine,CholesterolandCAD(1)•Keys(1958)publisheddatathatcountrieswiththehighestcholesterollevelshadthehighestrateofcardiovasculardisease•FinlandhadthehighestrateofCADmortalityinEurope•Moreprevalen

6、tinEasternFinlandvs.WesternFinlandWHY?Lancet.2:175-78.1958Iodine,CholesterolandCAD(2)•Researcherslookedatavarietyofdietarycomponents•Proteins,fats,carbohydrates,lipids,aminoacids,vitaminsandminerals•47differentitemsstudiedIodineintakeshowedthegreateststatisticaldifferencebetweenEasternandWesternFinl

7、andRiskofdeathfromCADwas353%higherinindividualswithgoiter.Therewasalsoasignificantlylowereddeathageinthosewithgoiter.Lancet.2:171-3.1958FinlandandCAD:1970•Researcherslookedatprevalenceofcardiovascular