nk memory外语英文电子书

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1、NKCellsandImmune''Memory''JosephC.Sun,SandraLopez-Verges,CharlesC.Kim,JosephL.DeRisiandLewisL.LanierThisinformationiscurrentasJImmunol2011;186;1891-1897ofApril15,2011doi:10.4049/jimmunol.1003035http://www.jimmunol.org/content/186/4/1891ReferencesThisarticlecites88articles,37ofwhichc

2、anbeaccessedfreeat:http://www.jimmunol.org/content/186/4/1891.full.html#ref-list-1DownloadedfromSubscriptionsInformationaboutsubscribingtoTheJournalofImmunologyisonlineathttp://www.jimmunol.org/subscriptionsPermissionsSubmitcopyrightpermissionrequestsathttp://www.aai.org/ji/copyrigh

3、t.htmlEmailAlertsReceivefreeemail-alertswhennewarticlescitethisarticle.Signupatwww.jimmunol.orghttp://www.jimmunol.org/etoc/subscriptions.shtml/onApril15,2011TheJournalofImmunologyispublishedtwiceeachmonthbyTheAmericanAssociationofImmunologists,Inc.,9650RockvillePike,Bethesda,MD2081

4、4-3994.Copyright©2011byTheAmericanAssociationofImmunologists,Inc.Allrightsreserved.PrintISSN:0022-1767OnlineISSN:1550-6606.NKCellsandImmune“Memory”,1†,1‡‡JosephC.Sun,*SandraLopez-Verges,CharlesC.Kim,JosephL.DeRisi,†andLewisL.LanierImmunologicalmemoryisahallmarkoftheadaptivepersistfo

5、rmonthstoyears,makingimmunememoryunim-immunesystem.However,theabilitytorememberportant,orunnecessary,forshort-livedcellscomprisingtheandrespondmorerobustlyagainstasecondencounterinnateimmunesystem,suchasgranulocytesanddendriticcellswiththesamepathogenhasbeendescribedinorganisms(DCs)

6、.Althoughfrequentlydiscussedinisolation,thesetwolackingTandBcells.Recently,NKcellshavebeensidesoftheimmunesystemrarelyactinisolation,andtheshowntomediateAg-specificrecallresponsesinseveralinterplaybetweencellsoftheinnateandadaptiveimmunedifferentmodelsystems.AlthoughNKcellsdonotrear-

7、armscontributestothemostproductiveoverallresponsesrangethegenesencodingtheiractivatingreceptors,NKagainstpathogeninvasion.cellsexperienceaselectiveeducationprocessduringde-velopment,undergoaclonal-likeexpansionduringvi-EvidenceforinnateimmunememoryDownloadedfromrusinfection,generate

8、long-livedprogeny(i