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1、多云转晴240ThecharacterofpublicsupportforuseofanimalsinbiomedicalresearchishighlyvariableHowisthepollingquestionasked?Whoasksthequestion;whoisasked?Doesthequestionstatewhetherpossibleanimalpainordistressisapartoftheresearch?Educationis,sadly,deficient.Theprotocolreviewprocess(simplif
2、ied)AAALAC:AssociationfortheAssessmentandAccreditationofLaboratoryAnimalCareNotregulatory,butevaluatesthequalityofaprogram;providesanindependent“sealofapproval”Graduate(includesPrimateCenter),Medical,andVeterinarySchoolsatUW-MadisonareaccreditedCALSandL&Shavemadethedecisi
3、ontobecomeaccreditedTheethicsofanimaluseUtilitarianism:theviewthatanactionisrightifandonlyifitproducesabetterbalanceofbenefitsandharmsthanavailablealternativeactionsConsiderthe“U.S.GovernmentPrinciplesfortheUtilizationandCareofVertebrateAnimalsUsedinTesting,Research,andTraining”U
4、.SGovernmentPrinciples(summary)Proceduresinvolvinganimalsshouldbedesignedandperformedwithdueconsiderationoftheirrelevancetohumanoranimalhealth,theadvancementofknowledge,orthegoodofsociety.Theanimalsselectedforaprocedureshouldbeofanappropriatespeciesandqualityandtheminimumnumberre
5、quiredtoobtainvalidresults.[Alternative]methods…shouldbeconsidered.Properuseofanimals,includingtheavoidanceorminimizationofdiscomfort,distress,andpainwhenconsistentwithsoundscientificpractices,isimperative.Procedureswithanimalsthatmaycausemorethanmomentaryorslightpainordistresssh
6、ouldbeperformedwithappropriatesedation,analgesia,oranesthesia.Animalsthatwouldotherwisesuffersevereorchronicpainordistressthatcannotberelievedshouldbepainlesskilledattheendoftheprocedureor,ifappropriate,duringtheprocedure.U.SGovernmentPrinciples(continued)Thelivingconditionsofani
7、malsshouldbeappropriatefortheirspeciesandcontributetotheirhealthandcomfort….veterinarycareshallbeprovidedasindicated.Investigatorsandotherpersonnelshallbeappropriatelyqualifiedandexperiencedforconductingproceduresonlivinganimals.…exceptions…shouldbemadeby…anappropriatereviewgroup
8、suchasanIACUCUtilitarianism!Steward