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1、探究围产期酮病奶牛高糖现象摘要：本文主要以黑龙江省某集约化奶牛场的产后14、21天69头奶牛为对象，旨在通过对围产期酮病病程长短分组探究围产期酮病高血糖现象。根据血浆BHBA浓度，将实验牛分成酮病组（K）和健康对照组（C）。在酮病组中将产后14和21天都发病的分为病程长组（LTK），将产后14和21天中仅一个时间点发病的分为病程短组(STK)。分别检测其GLU、NEFA、BHBA、肝功能指标，分析结果显示：①围产期高血糖现象主要集中在STK组中；②LTK组BHBA极显著高于STK组和C组。LTK组和STK组NEFA极显著高于C组，而LTK组与S
2、TK组之间差异不显著。LTK组Glu显著低于C组和STK组,而STK组与C组之间无显著差异。结论：酮病奶牛机体处于能量负平衡状态。病程短的酮病奶牛能量负平衡的程度轻，代偿机能强，可维持血糖在正常水平，而病程长的酮病奶牛则相反。并且病程长的酮病奶牛肝脏功能状况发生了明显的变化，而病程短的酮病奶牛肝脏功能表现基本正常。关键词：奶牛；围产期；酮病；高血糖；肝功能StudyofperinataldairyketosishyperglycemiaphenomenonAbstractThispapermainlyanintensivedairyfarmin
3、Heilongjiangprovinceofpostpartum14,21daysand69cowsastheobject,aimstoperinatalketosisdurationgroupstoexploreperinatalketosishyperglycemia.AccordingtotheplasmaconcentrationofBHBA,thecattleintoketosisgroup(K)andhealthycontrolgroup(C).Inketosisgroup,14and21dayspostpartumonsetisd
4、ividedintolongcoursegroup(LTK),14and21dayspostpartuminonlyonepointintimetheonsetofdividedintoshortcourseofdiseasegroup(STK).TodetecttheirGLU,NEFA,BHBA,liverfunctionindex,analysisoftheresultsshowedthat:①perinatalhyperglycemiamainlyconcentratedintheSTKgroup;BHBAofLTKgroupwassi
5、gnificantlyhigherthanthatinSTKgroupandCgroup.LTKgroupandSTKgroupNEFAissignificantlyhigherthanthatofgroupC,andbetweenLTKgroupandSTKgroup,thedifferencewasnotsignificant.TheLTKingroupGluwassignificantlylowerthanthatofCgroupandSTKgroup,butnosignificantdifferencebetweengroupSTKan
6、dgroupC.Conclusion:ketosiscowsinnegativeenergybalanceofthebody.Ashortcourseofketosiscowsinnegativeenergybalancedegreeoflight,compensatoryfunctionstrong,canbemaintainedinthenormallevelofbloodsugar,andlongerdurationofcowketosisisopposite.Andthelongerdurationofketosisindairycow
7、liverfunctionchangedobviously,andketosiscowsliverfunctionofshortdurationofnormal.Keywords:cow;perinatal;ketosis;hyperglycemia;liverfunction奶牛酮病是奶牛由于体内碳水化合物及挥发性脂肪酸代谢紊乱所引起的一种全身性功能失调的营养代谢性疾病，其特征是低血糖、高血酮、尿酮和乳酮，呼出气体以及乳汁带有丙酮气味，消化机能紊乱，体重减轻，产奶量下降，个别牛出现神经症状。【江精华.奶牛酮病致病机理研究[D].广西大学.20
8、06-05-01】。按照临床表现和酮体水平通常分为临床酮病和亚临床酮病【李艳鸽.奶牛酮病的研究综述[J].畜禽业.2011年第6期】。目前，国外提出将
