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1、……………………………………………………………最新资料推荐…………………………………………………Adefovirdipivoxil for the treatmentofchronichepatitisBclinicalobservation Abstract:Objective: Toinvestigateadefovirdipivoxilclinicalefficacy andadverseeffectsoftreatmentofchronichepatitis B. Methods:Sele
2、ctfromJune2010toJune 2011chronic hepatitisB patientsadmittedtoourhospital,98cases,wererandomly divided49casesforeachof theobservationgroupandthecontrolgroup,thecontrolgroupofpatientsgivenbicyclol100 mg/ d, ursodeoxycholicacid250 mg/d,oneday,onceeverys
3、ixmonths,to observepatientsinthecontrolgrouptreatmentgivenonthebasis ofadefovirdipivoxil10mg/ d,twiceaday,once every6months after theendoftreatment,theclinicalefficacyofthetwogroupswerecompared, the observedimprovementinliverfunction indicatorsandadve
4、rsedrugreaction. Results:The treatmentaftertheendof the8/8……………………………………………………………最新资料推荐…………………………………………………observationgroup, thetotal effectiveratewas90。77%,significantly higherthan72.31%, the differencewasstatisticallysignificant(χ 2=5。796,P<0.05.o
5、bservationgroup, alanineaminotransferase(ALT, aspartateaminotransferase(AST,serumalbumin(ALB,serumtotal bilirubin(TBiLrecoveryconditionsarebetterthanthe control group,the differenceswerestatisticallysignificant (P <0。05, afterthe endoftreatment,the
6、twogroupswerenotliver deterioration ofrenal function andotheradversereactions,adverse reactions differencesnotstatisticallysignificant(P&gt;0。05.Conclusion:Adefovirdipivoxil treatment of chronic hepatitisB patientswithsignificantliverfunction recovery
7、,nosignificant adversereactionsoccurredworthyofclinicalpromote the useof。
ﻪ Keywords:chronic hepatitisB,adefovirdipivoxil,clinicalefficacyHepatitis B is oneofthemajordiseasesthreateningtheglobalhumanhealthhasbeen8/8……………………………………………………………最新资料推荐………………
8、…………………………………reportedthatthe5-yearsurvivalrateofonly 14%[1]this article theauthorused the co—administrationofadefovir dipivoxiltreatment ofchronic hepatitis B,andachieved satisfactory effect,are reported asfollows:ﻭ1MaterialsandMethods1。1Gener